Dihydropyrimidinase-related protein 1

UniProtKB accession:  P97427

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (PubMed:14685275, PubMed:25358863). Plays a role in axon guidance (PubMed:14685275). During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone (PubMed:25358863). Involved in invasive growth and cell migration (By similarity). May participate in cytokinesis (By similarity).