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Explore in 3D: Sequence Alignments
3J7Y_34 - Summary | Structure
Name: Large ribosomal subunit protein mL41
Organism: Homo sapiens
Experimental Method: EM
Resolution: 3.4 Å
Molecular Weight: 15.405 kDa

Large ribosomal subunit protein mL41

UniProtKB accession:  Q8IXM3
Grouped By:  Matching UniProtKB accession
Group Content:  
Polymer Entities matching query 69
Go to UniProtKB:  Q8IXM3
UniProtKB description:  Component of the mitochondrial ribosome large subunit (PubMed:25278503, PubMed:25838379, PubMed:28892042, PubMed:35177605). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed:16024796).
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Experimental Features
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Protein Domains
ECOD Domain
PFAM Domain
InterPro Domain


Function
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