RCSB PDB: Search

2ATV \| pdb_00002atv	Download File View File

The crystal structure of human RERG in the GDP bound state

Turnbull, A.P., Salah, E., Schoch, G., Elkins, J., Burgess, N., Gileadi, O., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)

To be published

Released	2005-10-18
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	RAS-like estrogen-regulated growth inhibitor (protein)
Unique Ligands	GDP, MG

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2B05 \| pdb_00002b05	Download File View File

Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide

Papagrigoriou, E., Elkins, J., Arrowsmith, C., Zhao, Y., Debreczeni, E.J., Edwards, A., Weigelt, J., Doyle, D., von Delft, F., Turnbull, A., Yang, X.

To be published

Released	2005-10-11
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Homo sapiens
Macromolecule	14-3-3 protein gamma (protein) peptide (protein)

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2C2H \| pdb_00002c2h	Download File View File

CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP

Debreczeni, J.E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., von Delft, F., Doyle, D., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.

To be published

Released	2005-10-13
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3 (protein)
Unique Ligands	CA, GDP, MG, SO4

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2CLS \| pdb_00002cls	Download File View File

The crystal structure of the human RND1 GTPase in the active GTP bound state

Pike, A.C.W., Yang, X., Colebrook, S., Gileadi, O., Sobott, F., Bray, J., Wen Hwa, L., Marsden, B., Zhao, Y., Schoch, G., Elkins, J., Debreczeni, J.E., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.

To be published

Released	2006-05-04
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Homo sapiens
Macromolecule	RHO-RELATED GTP-BINDING PROTEIN RHO6 (protein)
Unique Ligands	GTP, MG

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2ERX \| pdb_00002erx	Download File View File

Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate

Papagrigoriou, E., Yang, X., Elkins, J., Niesen, F.E., Burgess, N., Salah, E., Fedorov, O., Ball, L.J., von Delft, F., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Doyle, D.

To be published

Released	2005-11-01
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	GTP-binding protein Di-Ras2 (protein)
Unique Ligands	GDP, MG, PO4

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2ERY \| pdb_00002ery	Download File View File

The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state

Salah, E., Schoch, G., Turnbull, A., Papagrigoriou, E., Soundararajan, M., Burgess, N., Elkins, J., Gileadi, C., Gileadi, O., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)

To be published

Released	2005-11-08
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Ras-related protein R-Ras2 (protein)
Unique Ligands	GDP, MG

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2F5Y \| pdb_00002f5y	Download File View File

Crystal Structure of the PDZ Domain from Human RGS-3

Ugochukwu, E., Berridge, G., Johansson, C., Smee, C., Savitsky, P., Burgess, N., Colebrook, S., Yang, X., Elkins, J., Doyle, D., Turnbull, A., Papagrigoriou, E., Debreczeni, J., Bunkoczi, G., Gorrec, F., von Delft, F., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)

To be published

Released	2005-12-13
Method	X-RAY DIFFRACTION 2.39 Å
Organisms	Homo sapiens
Macromolecule	regulator of G-protein signalling 3 isoform 1 (protein)
Unique Ligands	SO4

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2FE5 \| pdb_00002fe5	Download File View File

The Crystal Structure of the Second PDZ Domain of Human DLG3

Ugochukwu, E., Phillips, C., Schoch, G., Berridge, G., Salah, E., Colebrook, S., Smee, C., Savitsky, P., Bray, J., Elkins, J., Doyle, D., Bunkoczi, G., Debreczeni, J., Turnbull, A., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)

To be published

Released	2005-12-27
Method	X-RAY DIFFRACTION 1.1 Å
Organisms	Homo sapiens
Macromolecule	Presynaptic protein SAP102 (protein)
Unique Ligands	GOL, SO4

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2G0N \| pdb_00002g0n	Download File View File

The Crystal Structure of the Human RAC3 in complex with GDP and Chloride

Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)

To be published

Released	2006-05-30
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Ras-related C3 botulinum toxin substrate 3 (protein)
Unique Ligands	CL, GDP, MG

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2G3Y \| pdb_00002g3y	Download File View File

Crystal structure of the human small GTPase GEM

Ugochukwu, E., Soundararajan, M., Elkins, J., Gileadi, C., Schoch, G., Sobott, F., Fedorov, O., Bray, J., Pantic, N., Berridge, G., Burgess, N., Lee, W.H., Turnbull, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)

To be published

Released	2006-04-18
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	GTP-binding protein GEM (protein)
Unique Ligands	GDP

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2GF0 \| pdb_00002gf0	Download File View File

The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state

Turnbull, A.P., Papagrigoriou, E., Yang, X., Schoch, G., Elkins, J., Gileadi, O., Salah, E., Bray, J., Wen-Hwa, L., Fedorov, O., Niesen, F.E., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)

To be published

Released	2006-04-04
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	GTP-binding protein Di-Ras1 (protein)
Unique Ligands	GDP, MG

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2H63 \| pdb_00002h63	Download File View File

Crystal Structure of Human Biliverdin Reductase A

Kavanagh, K., Elkins, J., Ugochukwu, E., Guo, K., Pilka, E., Lukacik, P., Smee, C., Papagrigoriou, E., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2006-07-04
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	Biliverdin reductase A (protein)
Unique Ligands	NAP

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2I1N \| pdb_00002i1n	Download File View File

Crystal structure of the 1st PDZ domain of Human DLG3

Turnbull, A.P., Phillips, C., Bunkoczi, G., Debreczeni, J., Ugochukwu, E., Pike, A.C.W., Gorrec, F., Umeano, C., Elkins, J., Berridge, G., Savitsky, P., Gileadi, O., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)

(2007) Protein Sci 16: 683-694

Released	2006-09-05
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Discs, large homolog 3 (protein)
Unique Ligands	NA

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2I59 \| pdb_00002i59	Download File View File

Solution structure of RGS10

Fedorov, O., Higman, V.A., Diehl, A., Leidert, M., Lemak, A., Schmieder, P., Oschkinat, H., Elkins, J., Soundarajan, M., Doyle, D.A., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Ball, L.J., Structural Genomics Consortium (SGC)

(2008) Proc Natl Acad Sci U S A 105: 6457-6462

Released	2006-10-31
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Regulator of G-protein signaling 10 (protein)

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2IC5 \| pdb_00002ic5	Download File View File

Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.

Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)

To be published

Released	2006-10-10
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Ras-related C3 botulinum toxin substrate 3 (protein)
Unique Ligands	BTB, CL, GDP, GNP, MG

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2IHD \| pdb_00002ihd	Download File View File

Crystal structure of Human Regulator of G-protein signaling 8, RGS8

Turnbull, A.P., Papagrigoriou, E., Ugochukwu, E., Salah, E., Gileadi, C., Burgess, N., Bhatia, C., Gileadi, O., Bray, J., Elkins, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)

(2008) Proc Natl Acad Sci U S A 105: 6457-6462

Released	2006-11-21
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Regulator of G-protein signaling 8 (protein)
Unique Ligands	CL

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2J1L \| pdb_00002j1l	Download File View File

Crystal Structure of Human Rho-related GTP-binding protein RhoD

Pike, A.C.W., Johansson, C., Gileadi, C., Niesen, F.H., Sobott, F., Schoch, G., Elkins, J., Smee, C., Gorrec, F., Watt, S., Bray, J., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.

To be published

Released	2006-09-18
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	RHO-RELATED GTP-BINDING PROTEIN RHOD (protein)
Unique Ligands	GDP, MG

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2JIK \| pdb_00002jik	Download File View File

Crystal structure of PDZ domain of Synaptojanin-2 binding protein

Tickle, J., Phillips, C., Pike, A.C.W., Cooper, C., Salah, E., Elkins, J., Turnbull, A.P., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.

To be published

Released	2007-07-10
Method	X-RAY DIFFRACTION 1.35 Å
Organisms	Homo sapiens
Macromolecule	SYNAPTOJANIN-2 BINDING PROTEIN (protein)

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2JIL \| pdb_00002jil	Download File View File

Crystal structure of 2nd PDZ domain of glutamate receptor interacting protein-1 (GRIP1)

Tickle, J., Elkins, J., Pike, A.C.W., Cooper, C., Salah, E., Papagrigoriou, E., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.

To be published

Released	2007-07-10
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	GLUTAMATE RECEPTOR INTERACTING PROTEIN-1 (protein)
Unique Ligands	EDO, SCN

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2JIN \| pdb_00002jin	Download File View File

Crystal structure of PDZ domain of Synaptojanin-2 binding protein

Tickle, J., Phillips, C., Pike, A.C.W., Cooper, C., Salah, E., Elkins, J., Turnbull, A.P., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.

To be published

Released	2007-07-10
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	SYNAPTOJANIN-2 BINDING PROTEIN (protein)
Unique Ligands	NA, SO4

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2JM5 \| pdb_00002jm5	Download File View File

Solution Structure of the RGS domain from human RGS18

Higman, V.A., Leidert, M., Bray, J., Elkins, J., Soundararajan, M., Doyle, D.A., Gileadi, C., Phillips, C., Schoch, G., Yang, X., Brockmann, C., Schmieder, P., Diehl, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oschkinat, H., Ball, L.J., Structural Genomics Consortium (SGC)

(2008) Proc Natl Acad Sci U S A 105: 6457-6462

Released	2006-10-24
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Regulator of G-protein signaling 18 (protein)

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2JNU \| pdb_00002jnu	Download File View File

Solution structure of the RGS domain of human RGS14

Dowler, E.F., Diehl, A., Bray, J., Elkins, J., Soundararajan, M., Doyle, D.A., Gileadi, C., Phillips, C., Schoch, G.A., Yang, X., Brockmann, C., Leidert, M., Rehbein, K., Schmieder, P., Kuhne, R., Higman, V.A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oschkinat, H., Ball, L.J., Structural Genomics Consortium (SGC)

(2008) Proc Natl Acad Sci U S A 105: 6457-6462

Released	2007-02-27
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Regulator of G-protein signaling 14 (protein)

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2O2T \| pdb_00002o2t	Download File View File

The crystal structure of the 1st PDZ domain of MPDZ

Papagrigoriou, E., Gileadi, C., Phillips, C., Johansson, C., Salah, E., Savitsky, P., Gorrec, F., Umeano, C., Berridge, G., Pike, A.C.W., Elkins, J., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)

To be published

Released	2006-12-12
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	Multiple PDZ domain protein (protein)

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2OCS \| pdb_00002ocs	Download File View File

The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)

Papagrigoriou, E., Phillips, C., Gileadi, C., Elkins, J., Salah, E., Berridge, G., Savitsky, P., Gorrec, F., Umeano, C., Ugochukwu, E., Gileadi, O., Burgess, N., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)

To be published

Released	2007-01-16
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (protein)
Unique Ligands	EDO, SCN

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2ODB \| pdb_00002odb	Download File View File

The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6)

Ugochukwu, E., Yang, X., Elkins, J., Soundararajan, M., Pike, A.C.W., Eswaran, J., Burgess, N., Debreczeni, J.E., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Gileadi, O., von Delft, F., Knapp, S., Doyle, D., Structural Genomics Consortium (SGC)

To be published

Released	2007-01-30
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Human Cell Division Cycle 42 (CDC42) (protein) Serine/threonine-protein kinase PAK 6 (protein)
Unique Ligands	CL, GCP, MG, SO4

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Scientific Name of Source Organism

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Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

2ATV | pdb_00002atv

2B05 | pdb_00002b05

2C2H | pdb_00002c2h

2CLS | pdb_00002cls

2ERX | pdb_00002erx

2ERY | pdb_00002ery

2F5Y | pdb_00002f5y

2FE5 | pdb_00002fe5

2G0N | pdb_00002g0n

2G3Y | pdb_00002g3y

2GF0 | pdb_00002gf0

2H63 | pdb_00002h63

2I1N | pdb_00002i1n

2I59 | pdb_00002i59

2IC5 | pdb_00002ic5

2IHD | pdb_00002ihd

2J1L | pdb_00002j1l

2JIK | pdb_00002jik

2JIL | pdb_00002jil

2JIN | pdb_00002jin

2JM5 | pdb_00002jm5

2JNU | pdb_00002jnu

2O2T | pdb_00002o2t

2OCS | pdb_00002ocs

2ODB | pdb_00002odb