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232,829 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Masic, V."

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Search Summary

This query matches 15 Structures.

Refinements

Structure Determination Methodology

experimental (15)

Scientific Name of Source Organism

	Homo sapiens (8)
	Escherichia coli (3)
	Bacillus subtilis (1)
	Bacteroides thetaiotaomicron (1)
	Pseudomonas corrugata (1)
	Streptococcus equi (1)

Taxonomy

	Eukaryota (8)
	Bacteria (7)

Experimental Method

X-RAY DIFFRACTION (15)

Polymer Entity Type

Protein (15)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (11)
	2.0 - 2.5 (1)
	2.5 - 3.0 (1)
	3.0 - 3.5 (1)

Release Date

2020 - 2024 (15)

Enzyme Classification Name

	Transferases (8)
	Hydrolases (3)

Symmetry Type

	Asymmetric (9)
	Cyclic (5)
	Dihedral (1)

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1 to 15 of 15 Structures

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7SE6	Download File View File

Crystal structure of human Fibrillarin in ligand-free state

Shi, Y., El-Deeb, I.M., Masic, V., Hartley-Tassell, L., Maggioni, A., von Itzstein, M., Ve, T.

(2021) Pharmaceuticals (Basel) 15:

Released	2022-02-09
Method	X-RAY DIFFRACTION 1.99 Å
Organisms	Homo sapiens
Macromolecule	rRNA 2'-O-methyltransferase fibrillarin (protein)
Unique Ligands	FMT

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7SE7	Download File View File

Crystal structure of human Fibrillarin in complex with S-adenosyl-L-methionine

Shi, Y., El-Deeb, I.M., Masic, V., Hartley-Tassell, L., Maggioni, A., von Itzstein, M., Ve, T.

(2021) Pharmaceuticals (Basel) 15:

Released	2022-02-09
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Homo sapiens
Macromolecule	rRNA 2'-O-methyltransferase fibrillarin (protein)
Unique Ligands	SAM

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7SE8	Download File View File

Crystal structure of human Fibrillarin in complex with fragment 1 from cocktail soak

Shi, Y., El-Deeb, I.M., Masic, V., Hartley-Tassell, L., Maggioni, A., von Itzstein, M., Ve, T.

(2021) Pharmaceuticals (Basel) 15:

Released	2022-02-09
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Homo sapiens
Macromolecule	rRNA 2'-O-methyltransferase fibrillarin (protein)
Unique Ligands	8W1, DMS, FMT

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7SE9	Download File View File

Crystal structure of human Fibrillarin in complex with compound 1 from single soak

Shi, Y., El-Deeb, I.M., Masic, V., Hartley-Tassell, L., Maggioni, A., von Itzstein, M., Ve, T.

(2021) Pharmaceuticals (Basel) 15:

Released	2022-02-09
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Homo sapiens
Macromolecule	rRNA 2'-O-methyltransferase fibrillarin (protein)
Unique Ligands	8W1, DMS, FMT

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7SEA	Download File View File

Crystal structure of human Fibrillarin in complex with compound 2 from cocktail soak

Shi, Y., El-Deeb, I.M., Masic, V., Hartley-Tassell, L., Maggioni, A., von Itzstein, M., Ve, T.

(2021) Pharmaceuticals (Basel) 15:

Released	2022-02-09
Method	X-RAY DIFFRACTION 1.91 Å
Organisms	Homo sapiens
Macromolecule	rRNA 2'-O-methyltransferase fibrillarin (protein)
Unique Ligands	8XF, DMS, FMT

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7SEB	Download File View File

Crystal structure of human Fibrillarin in complex with compound 2 from single soak

Shi, Y., El-Deeb, I.M., Masic, V., Hartley-Tassell, L., Maggioni, A., von Itzstein, M., Ve, T.

(2021) Pharmaceuticals (Basel) 15:

Released	2022-02-09
Method	X-RAY DIFFRACTION 1.81 Å
Organisms	Homo sapiens
Macromolecule	rRNA 2'-O-methyltransferase fibrillarin (protein)
Unique Ligands	8XF, FMT

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7SEC	Download File View File

Crystal structure of human Fibrillarin in complex with compound 1a

Shi, Y., El-Deeb, I.M., Masic, V., Hartley-Tassell, L., Maggioni, A., von Itzstein, M., Ve, T.

(2021) Pharmaceuticals (Basel) 15:

Released	2022-02-09
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	rRNA 2'-O-methyltransferase fibrillarin (protein)
Unique Ligands	8WP, DMS, FMT

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7SED	Download File View File

Crystal structure of human Fibrillarin in complex with compound 2a

Shi, Y., El-Deeb, I.M., Masic, V., Hartley-Tassell, L., Maggioni, A., von Itzstein, M., Ve, T.

(2021) Pharmaceuticals (Basel) 15:

Released	2022-02-09
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	rRNA 2'-O-methyltransferase fibrillarin (protein)
Unique Ligands	8VD, FMT

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7UXR	Download File View File

Crystal structure of the BtTir TIR domain

Shi, Y., Masic, V., Mosaiab, T., Vasquez, E., Ve, T.

(2022) Science 377: eadc8969-eadc8969

Released	2022-09-07
Method	X-RAY DIFFRACTION 1.42 Å
Organisms	Bacteroides thetaiotaomicron
Macromolecule	TIR domain protein (protein)

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7UXS	Download File View File

Crystal structure of the BcThsA SLOG domain in complex with 3'cADPR

Shi, Y., Masic, V., Mosaiab, T., Ve, T.

(2022) Science 377: eadc8969-eadc8969

Released	2022-09-07
Method	X-RAY DIFFRACTION 1.57 Å
Organisms	Bacillus subtilis
Macromolecule	BcThsA (protein)
Unique Ligands	GOL, OJC, SO4

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7UXT	Download File View File

Crystal structure of ligand-free SeThsA

Shi, Y., Masic, V., Mosaiab, T., Nanson, J.D., Kobe, B., Ve, T.

(2022) Science 377: eadc8969-eadc8969

Released	2022-09-07
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Streptococcus equi
Macromolecule	USG protein (protein)
Unique Ligands	GOL, PGE

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8V6Q	Download File View File

Crystal structure of EcThsA in ligand-free state

Shi, Y., Masic, V., Mosaiab, T., Goulart, C.C., Hartley-Tassell, L., Sorbello, M., Vasquez, V., Mishra, B.P., Holt, S., Gu, W., Kobe, B., Ve, T.

(2024) Sci Adv 10: eadn3310-eadn3310

Released	2024-06-12
Method	X-RAY DIFFRACTION 2.62 Å
Organisms	Escherichia coli
Macromolecule	Thoeris protein ThsA Macro domain-containing protein (protein)

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8V6R	Download File View File

Crystal structure of EcThsA in complex with ADPR

Shi, Y., Masic, V., Mosaiab, T., Goulart, C.C., Hartley-Tassell, L., Sorbello, M., Vasquez, E., Mishra, B.P., Holt, S., Gu, W., Kobe, B., Ve, T.

(2024) Sci Adv 10: eadn3310-eadn3310

Released	2024-06-12
Method	X-RAY DIFFRACTION 2.14 Å
Organisms	Escherichia coli
Macromolecule	Thoeris protein ThsA Macro domain-containing protein (protein)
Unique Ligands	AR6

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8V6S	Download File View File

Crystal structure of PcThsA in complex with Imidazole Adenine Dinucleotide

Shi, Y., Masic, V., Mosaiab, T., Goulart, C.C., Hartley-Tassell, L., Sorbello, M., Vasquez, E., Mishra, B.P., Holt, S., Gu, W., Kobe, B., Ve, T.

(2024) Sci Adv 10: eadn3310-eadn3310

Released	2024-06-12
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Pseudomonas corrugata
Macromolecule	Thoeris protein ThsA Macro domain-containing protein (protein)
Unique Ligands	YG8