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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Miles, L.A."

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Search Summary

This query matches 13 Structures.

Refinements

Structure Determination Methodology

experimental (13)

Scientific Name of Source Organism

	Homo sapiens (10)
	Mus musculus (7)
	Conus gloriamaris (1)

Taxonomy

	Eukaryota (12)
	Eukaryota (eukaryotes) (3)

Experimental Method

	X-RAY DIFFRACTION (12)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (13)

Refinement Resolution (Å)

	1.5 - 2.0 (8)
	2.0 - 2.5 (4)

Release Date

	2000 - 2004 (1)
	2005 - 2009 (4)
	2010 - 2014 (2)
	2015 - 2019 (6)

Membrane Protein Annotation

OPM (1)

Symmetry Type

Asymmetric (13)

SCOP Classification

	All beta proteins (8)
	Artifacts (1)
	All alpha proteins (1)
	Small proteins (1)

AllSelected

1 to 13 of 13 Structures

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1IXT \| pdb_00001ixt	Download File View File

Structure of a Novel P-Superfamily Spasmodic Conotoxin Reveals an Inhibitory Cystine Knot Motif

Miles, L.A., Dy, C.Y., Nielsen, J., Barnham, K.J., Hinds, M.G., Olivera, B.M., Bulaj, G., Norton, R.S.

(2002) J Biological Chem 277: 43033-43040

Released	2003-01-28
Method	SOLUTION NMR
Organisms	Conus gloriamaris
Macromolecule	spasmodic protein tx9a-like protein (protein)

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3BAE \| pdb_00003bae	Download File View File

Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28)

Miles, L.A., Wun, K.S., Crespi, G.A., Parker, M.W.

(2008) J Mol Biology 377: 181-192

Released	2008-04-15
Method	X-RAY DIFFRACTION 1.593 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Amyloid Beta Peptide (protein) WO2 IgG2a Fab fragment Heavy Chain (protein) WO2 IgG2a Fab fragment Light Chain Kappa (protein)

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3BKC \| pdb_00003bkc	Download File View File

Crystal structure of anti-amyloid beta FAB WO2 (P21, FormB)

Miles, L.A., Wun, K.S., Crespi, G.A., Fodero-Tavoletti, M., Galatis, D., Bageley, C.J., Beyreuther, K., Masters, C.L., Cappai, R., McKinstry, W.J., Barnham, K.J., Parker, M.W.

(2008) J Mol Biology 377: 181-192

Released	2008-04-15
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Mus musculus
Macromolecule	WO2 IgG2a Fab fragment Heavy Chain (protein) WO2 IgG2a Fab fragment Light Chain Kappa (protein)
Unique Ligands	NA

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3BKJ \| pdb_00003bkj	Download File View File

Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16)

Miles, L.A., Wun, K.S., Crespi, G.A., Fodero-Tavoletti, M., Galatis, D., Bageley, C.J., Beyreuther, K., Masters, C.L., Cappai, R., McKinstry, W.J., Barnham, K.J., Parker, M.W.

(2008) J Mol Biology 377: 181-192

Released	2008-04-15
Method	X-RAY DIFFRACTION 1.59 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Amyloid Beta Peptide (protein) WO2 IgG2a Fab fragment Heavy Chain (protein) WO2 IgG2a Fab fragment Light Chain Kappa (protein)

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3BKM \| pdb_00003bkm	Download File View File

Structure of anti-amyloid-beta Fab WO2 (Form A, P212121)

Miles, L.A., Wun, K.S., Crespi, G.A., Fodero-Tavoletti, M., Galatis, D., Bageley, C.J., Beyreuther, K., Masters, C.L., Cappai, R., McKinstry, W.J., Barnham, K.J., Parker, M.W.

(2008) J Mol Biology 377: 181-192

Released	2008-04-15
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Mus musculus
Macromolecule	WO2 IgG2a Fab fragment Heavy Chain (protein) WO2 IgG2a Fab fragment Light Chain Kappa (protein)
Unique Ligands	NA, ZN

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3U0W \| pdb_00003u0w	Download File View File

AD related murine antibody Fragment

Miles, L.A., Crespi, G.A.N., Parker, M.W.

To be published

Released	2012-10-03
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Fab Heavy Chain, Ig gamma-1 chain C region (protein) Fab Light Chain, Ig kappa chain C region (protein)

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4HIX \| pdb_00004hix	Download File View File

Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide

Miles, L.A., Crespi, G.A.N., Parker, M.W.

(2013) Sci Rep 3: 1302-1302

Released	2013-03-13
Method	X-RAY DIFFRACTION 2.204 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Beta-amyloid protein 40 (protein) Humanized 3D6 Fab heavy chain (protein) Humanized 3D6 Fab light chain (protein)

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4OJF \| pdb_00004ojf	Download File View File

Humanised 3D6 Fab complexed to amyloid beta 1-8

Miles, L.A., Crespi, G.A.N., Parker, M.W.

(2014) Acta Crystallogr F Struct Biol Commun 70: 374-377

Released	2015-01-28
Method	X-RAY DIFFRACTION 1.998 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Amyloid beta A4 protein (protein) Humanised 3D6 Fab Heavy Chain (protein) Humanised 3D6 Fab Light Chain (protein)

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4XXD \| pdb_00004xxd	Download File View File

Crystal Structure of mid-region amyloid beta capture by solanezumab

Hermans, S.J., Crespi, G.A.N., Parker, M.W., Miles, L.A.

(2015) Sci Rep 5: 9649-9649

Released	2015-04-29
Method	X-RAY DIFFRACTION 2.41 Å
Organisms	Homo sapiens
Macromolecule	Amyloid-beta fragment (protein) Fab Heavy Chain (protein) Fab Light Chain (protein)

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5BUO \| pdb_00005buo	Download File View File

A receptor molecule

Gao, C., Crespi, G.A.N., Gorman, M.A., Nero, T.L., Parker, M.W., Miles, L.A.

To be published

Released	2016-07-13
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Homo sapiens
Macromolecule	Amyloid beta A4 protein (protein)
Unique Ligands	ACT, CA, GOL, MG, SCN, SO4, ZN
Unique branched monosaccharides	IDS, SGN