RCSB PDB: Search

7GAV \| pdb_00007gav	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with MAT-POS-f7918075-2 (SARS2_MproA-x0854)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.77 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	CL, DMS, KFU

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7GAW \| pdb_00007gaw	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with MAT-POS-e194df51-1 (SARS2_MproA-x0862)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.812 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	CL, DMS, KG9

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7GAX \| pdb_00007gax	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with GAB-REV-70cc3ca5-4 (Mpro-x10019)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.71 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KJI

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7GAY \| pdb_00007gay	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with BEN-DND-031a96cc-8 (Mpro-x10022)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KJO

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7GAZ \| pdb_00007gaz	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with DUN-NEW-f8ce3686-14 (Mpro-x10049)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.753 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KL6

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7GB0 \| pdb_00007gb0	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with MAT-POS-c0143b99-1 (Mpro-x10082)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.423 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KLR

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7GB1 \| pdb_00007gb1	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with STE-KUL-2e0d2e88-2 (Mpro-x10150)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.289 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KMF

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7GB2 \| pdb_00007gb2	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with MED-COV-4280ac29-25 (Mpro-x10155)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KMX

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7GB3 \| pdb_00007gb3	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with DAV-CRI-3edb475e-6 (Mpro-x10172)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.379 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KNU

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7GB4 \| pdb_00007gb4	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with DAR-DIA-23aa0b97-6 (Mpro-x10178)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.865 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KO9

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7GB5 \| pdb_00007gb5	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with EDG-MED-0da5ad92-2 (Mpro-x10201)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.261 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KOI

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7GB6 \| pdb_00007gb6	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with JOR-UNI-2fc98d0b-12 (Mpro-x10236)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.84 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KP0

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7GB7 \| pdb_00007gb7	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with JOR-UNI-2fc98d0b-6 (Mpro-x10237)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.55 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KQ3

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7GB8 \| pdb_00007gb8	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with JAN-GHE-83b26c96-14 (Mpro-x10247)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.957 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KQL

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7GB9 \| pdb_00007gb9	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with JAN-GHE-83b26c96-11 (Mpro-x10248)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KQX

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7GBA \| pdb_00007gba	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with ANT-OPE-d972fbad-1 (Mpro-x10296)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.699 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KS0

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7GBB \| pdb_00007gbb	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with DAN-LON-a5fc619e-3 (Mpro-x10306)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.737 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KSI

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7GBC \| pdb_00007gbc	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with TRY-UNI-2eddb1ff-1 (Mpro-x10314)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.655 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KSX

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7GBD \| pdb_00007gbd	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with RAL-MED-2de63afb-2 (Mpro-x10322)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.78 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KT9

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7GBE \| pdb_00007gbe	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with JAG-UCB-a3ef7265-20 (Mpro-x10324)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.224 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KU6

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7GBF \| pdb_00007gbf	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with JAN-GHE-83b26c96-9 (Mpro-x10327)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.769 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KUU

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7GBG \| pdb_00007gbg	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with JAN-GHE-83b26c96-1 (Mpro-x10329)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.461 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KVF

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7GBH \| pdb_00007gbh	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with EDJ-MED-49816e9b-2 (Mpro-x10334)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.581 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KVO

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7GBI \| pdb_00007gbi	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with JAG-UCB-a3ef7265-3 (Mpro-x10338)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.291 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KVX

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7GBJ \| pdb_00007gbj	Download File View File

Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with MAT-POS-590ac91e-32 (Mpro-x10355)

Fearon, D., Aimon, A., Aschenbrenner, J.C., Balcomb, B.H., Bertram, F.K.R., Brandao-Neto, J., Dias, A., Douangamath, A., Dunnett, L., Godoy, A.S., Gorrie-Stone, T.J., Koekemoer, L., Krojer, T., Lithgo, R.M., Lukacik, P., Marples, P.G., Mikolajek, H., Nelson, E., Owen, C.D., Powell, A.J., Rangel, V.L., Skyner, R., Strain-Damerell, C.M., Thompson, W., Tomlinson, C.W.E., Wild, C., Walsh, M.A., von Delft, F.

(2023) Science 382: eabo7201-eabo7201

Released	2023-11-08
Method	X-RAY DIFFRACTION 1.549 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, KW9

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

7GAV | pdb_00007gav

7GAW | pdb_00007gaw

7GAX | pdb_00007gax

7GAY | pdb_00007gay

7GAZ | pdb_00007gaz

7GB0 | pdb_00007gb0

7GB1 | pdb_00007gb1

7GB2 | pdb_00007gb2

7GB3 | pdb_00007gb3

7GB4 | pdb_00007gb4

7GB5 | pdb_00007gb5

7GB6 | pdb_00007gb6

7GB7 | pdb_00007gb7

7GB8 | pdb_00007gb8

7GB9 | pdb_00007gb9

7GBA | pdb_00007gba

7GBB | pdb_00007gbb

7GBC | pdb_00007gbc

7GBD | pdb_00007gbd

7GBE | pdb_00007gbe

7GBF | pdb_00007gbf

7GBG | pdb_00007gbg

7GBH | pdb_00007gbh

7GBI | pdb_00007gbi

7GBJ | pdb_00007gbj