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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Filippakopoulos, P."

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Search Summary

This query matches 57 Structures.

Refinements

Structure Determination Methodology

experimental (57)

Scientific Name of Source Organism

	Homo sapiens (26)
	Rhodobacter capsulatus (5)
	Streptococcus pneumoniae D39 (5)
	Vibrio vulnificus (5)
	Dickeya dadantii 3937 (3)
	Gloeobacter violaceus (3)
	Gloeobacter violaceus PCC 7421 (2)
	Staphylococcus aureus (2)
	Woodchuck hepatitis virus (2)
	Acinetobacter baumannii (1)

More...

Taxonomy

	Bacteria (28)
	Eukaryota (26)
	Riboviria (2)
	other sequences (1)

Experimental Method

	X-RAY DIFFRACTION (56)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

	Protein (56)
	RNA (1)

Refinement Resolution (Å)

	1.0 - 1.5 (18)
	1.5 - 2.0 (9)
	2.0 - 2.5 (11)
	2.5 - 3.0 (9)
	3.0 - 3.5 (5)
	3.5 - 4.0 (3)
	4.0 - 4.5 (1)
	> 4.5 (1)

Release Date

	2010 - 2014 (6)
	2015 - 2019 (8)
	2020 - 2024 (43)

Enzyme Classification Name

	Hydrolases (12)
	Lyases (2)

Membrane Protein Annotation

	PDBTM (8)
	MemProtMD (7)
	OPM (4)
	mpstruc (2)

Symmetry Type

	Asymmetric (26)
	Cyclic (22)
	Dihedral (5)
	Icosahedral (1)

SCOP Classification

	All alpha proteins (8)
	Alpha and beta proteins (a/b) (7)
	Artifacts (7)
	All beta proteins (1)

AllSelected

1 to 25 of 57 Structures

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3UQ4 \| pdb_00003uq4	Download File View File

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant F247L (F16L)

Gonzalez-Gutierrez, G., Lukk, T., Agarwal, V., Papke, D., Nair, S.K., Grosman, C.

(2012) Proc Natl Acad Sci U S A 109: 6331-6336

Released	2012-04-04
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Dickeya dadantii 3937
Macromolecule	Gamma-aminobutyric-acid receptor subunit beta-1 (protein)
Unique Ligands	NA

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3UQ5 \| pdb_00003uq5	Download File View File

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant L240A F247L (L9A F16L) in the presence of 10 mM cysteamine

Gonzalez-Gutierrez, G., Lukk, T., Agarwal, V., Papke, D., Nair, S.K., Grosman, C.

(2012) Proc Natl Acad Sci U S A 109: 6331-6336

Released	2012-04-04
Method	X-RAY DIFFRACTION 4.2 Å
Organisms	Dickeya dadantii 3937
Macromolecule	Gamma-aminobutyric-acid receptor subunit beta-1 (protein)
Unique Ligands	NA

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3UQ7 \| pdb_00003uq7	Download File View File

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant L240S F247L (L9S F16L) in presence of 10 mM cysteamine

Gonzalez-Gutierrez, G., Lukk, T., Agarwal, V., Papke, D., Nair, S.K., Grosman, C.

(2012) Proc Natl Acad Sci U S A 109: 6331-6336

Released	2012-04-04
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Dickeya dadantii 3937
Macromolecule	Gamma-aminobutyric-acid receptor subunit beta-1 (protein)

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4LMJ \| pdb_00004lmj	Download File View File

GLIC Liganded-closed-channel Conformation, Mutant T25'A

Grosman, C., Gonzalez-Gutierrez, G.

(2013) Proc Natl Acad Sci U S A 110: 18716-18721

Released	2013-10-30
Method	X-RAY DIFFRACTION 3.44 Å
Organisms	Gloeobacter violaceus
Macromolecule	Proton-gated ion channel (protein)
Unique Ligands	CL, LMT, NA

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4LMK \| pdb_00004lmk	Download File View File

GLIC Liganded-closed-channel Conformation, Mutant Y27'A

Grosman, C., Gonzalez-Gutierrez, G.

(2013) Proc Natl Acad Sci U S A 110: 18716-18721

Released	2013-10-30
Method	X-RAY DIFFRACTION 3.22 Å
Organisms	Gloeobacter violaceus
Macromolecule	Proton-gated ion channel (protein)
Unique Ligands	CL, LMT, NA

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4LML \| pdb_00004lml	Download File View File

GLIC double mutant I9'A T25'A

Grosman, C., Gonzalez-Gutierrez, G.

(2013) Proc Natl Acad Sci U S A 110: 18716-18721

Released	2013-10-30
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Gloeobacter violaceus
Macromolecule	Proton-gated ion channel (protein)

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5V6N \| pdb_00005v6n	Download File View File

Crystal Structure of the highly open channel-stabilized mutant C27S + K33C + I9'A + N21'C of GLIC under reducing conditions.

Gonzalez-Gutierrez, G., Grosman, C.

(2017) J Gen Physiol 149: 1119-1138

Released	2017-10-18
Method	X-RAY DIFFRACTION 3.355 Å
Organisms	Gloeobacter violaceus PCC 7421
Macromolecule	Proton-gated ion channel (protein)
Unique Ligands	LMT, NA, SO4

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5V6O \| pdb_00005v6o	Download File View File

Crystal Structure of the highly open channel-stabilized mutant G-2'I + I9'A of GLIC

Gonzalez-Gutierrez, G., Grosman, C.

(2017) J Gen Physiol 149: 1119-1138

Released	2017-10-18
Method	X-RAY DIFFRACTION 3.121 Å
Organisms	Gloeobacter violaceus PCC 7421
Macromolecule	Proton-gated ion channel (protein)
Unique Ligands	CL, LMT, NA, SO4

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6CDA \| pdb_00006cda	Download File View File

Crystal structure of L34A CzrA in the Zn(II)bound state

Capdevila, D.A., Gonzalez-Gutierrez, G., Giedroc, D.P.

(2018) J Am Chem Soc 140: 9108-9119

Released	2018-07-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Staphylococcus aureus
Macromolecule	ArsR family transcriptional regulator (protein)
Unique Ligands	CL, GOL, PG4, ZN

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6CDB \| pdb_00006cdb	Download File View File

Crystal Structure of V66L CzrA in the Zn(II)bound state

Capdevila, D.A., Campanello, G., Gonzalez-Gutierrez, G., Giedroc, D.P.

(2018) J Am Chem Soc 140: 9108-9119

Released	2018-07-11
Method	X-RAY DIFFRACTION 1.99 Å
Organisms	Staphylococcus aureus
Macromolecule	ArsR family transcriptional regulator (protein)
Unique Ligands	CL, NA, PG4, ZN

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6E5G \| pdb_00006e5g	Download File View File

Crystal structure of human TEAD2-Yap binding domain covalently bound to an allosteric regulator

Bum-Erdene, K., Gonzalez-Gutierrez, G., Meroueh, S.O.

(2019) Cell Chem Biol 26: 378

Released	2019-01-09
Method	X-RAY DIFFRACTION 2.43 Å
Organisms	Homo sapiens
Macromolecule	Transcriptional enhancer factor TEF-4 (protein)
Unique Ligands	HUY

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6ECS \| pdb_00006ecs	Download File View File

Crystal structure of WHV core protein mutant Y132A dimer

Zhao, Z., Gonzalez-Gutierrez, G., Zlotnick, A.

(2019) J Virol 93:

Released	2019-05-01
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Woodchuck hepatitis virus
Macromolecule	External core antigen (protein)

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6EDJ \| pdb_00006edj	Download File View File

Cryo-EM structure of Woodchuck hepatitis virus capsid

Zhao, Z., Wang, J.C., Zlotnick, A.

(2019) J Virol 93:

Released	2019-05-01
Method	ELECTRON MICROSCOPY 4.52 Å
Organisms	Woodchuck hepatitis virus
Macromolecule	External core antigen (protein)

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6MNZ \| pdb_00006mnz	Download File View File

Crystal structure of RibBX, a two domain 3,4-dihydroxy-2-butanone 4-phosphate synthase from A. baumannii.

Wang, J., Gonzalez-Gutierrez, G., Giedroc, D.P.

(2019) Cell Chem Biol 26: 745

Released	2019-04-17
Method	X-RAY DIFFRACTION 2.66 Å
Organisms	Acinetobacter baumannii
Macromolecule	3,4-dihydroxy-2-butanone 4-phosphate synthase (protein)
Unique Ligands	CL, SO4

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6O8K \| pdb_00006o8k	Download File View File

Crystal Structure of apo and reduced Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulatus.

Capdevila, D.A., Gonzalez-Gutierrez, G., Giedroc, D.P.

(2021) Nat Chem Biol 17: 65-70

Released	2020-04-01
Method	X-RAY DIFFRACTION 2.12 Å
Organisms	Rhodobacter capsulatus
Macromolecule	Transcriptional regulator, ArsR family (protein)
Unique Ligands	GOL, SO4

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6O8L \| pdb_00006o8l	Download File View File

Crystal Structure of C9S apo and reduced Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulatus.

Capdevila, D.A., Gonzalez-Gutierrez, G., Giedroc, D.P.

(2021) Nat Chem Biol 17: 65-70

Released	2020-04-01
Method	X-RAY DIFFRACTION 1.36 Å
Organisms	Rhodobacter capsulatus
Macromolecule	Transcriptional regulator, ArsR family (protein)

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6O8M \| pdb_00006o8m	Download File View File

Crystal Structure of C9S apo Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulated bound to diamide (tetramethylazodicarboxamide).

Capdevila, D.A., Gonzalez-Gutierrez, G., Giedroc, D.P.

(2021) Nat Chem Biol 17: 65-70

Released	2020-04-01
Method	X-RAY DIFFRACTION 1.46 Å
Organisms	Rhodobacter capsulatus
Macromolecule	Transcriptional regulator, ArsR family (protein)
Unique Ligands	LSY

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6O8N \| pdb_00006o8n	Download File View File

Crystal Structure of C9S tetrasulfide state of Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulatus.

Capdevila, D.A., Gonzalez-Gutierrez, G., Giedroc, D.P.

(2021) Nat Chem Biol 17: 65-70

Released	2020-04-01
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Rhodobacter capsulatus
Macromolecule	Transcriptional regulator, ArsR family (protein)
Unique Ligands	SO4

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6O8O \| pdb_00006o8o	Download File View File

Crystal Structure of C9S disulfide state of Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulatus.

Capdevila, D.A., Gonzalez-Gutierrez, G., Giedroc, D.P.

(2021) Nat Chem Biol 17: 65-70

Released	2020-04-01
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Rhodobacter capsulatus
Macromolecule	Transcriptional regulator, ArsR family (protein)
Unique Ligands	CL, SO4

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6P0I \| pdb_00006p0i	Download File View File

Crystal structure of GDP-bound human RalA in a covalent complex with aryl sulfonyl fluoride compounds.

Bum-Erdene, K., Gonzalez-Gutierrez, G., Liu, D., Ghozayel, M.K., Xu, D., Meroueh, S.O.

(2020) Proc Natl Acad Sci U S A 117: 7131-7139

Released	2020-03-04
Method	X-RAY DIFFRACTION 1.18 Å
Organisms	Homo sapiens
Macromolecule	Ras-related protein Ral-A (protein)
Unique Ligands	ACT, CA, CL, EDO, GDP, GOL, NA, NL7