RCSB PDB: Search

1ICW \| pdb_00001icw	Download File View File

INTERLEUKIN-8, MUTANT WITH GLU 38 REPLACED BY CYS AND CYS 50 REPLACED BY ALA

Eigenbrot, C., Lowman, H.B., Chee, L., Artis, D.R.

(1997) Proteins 27: 556-566

Released	1997-03-12
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Homo sapiens
Macromolecule	INTERLEUKIN-8 (protein)

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1QE6 \| pdb_00001qe6	Download File View File

INTERLEUKIN-8 WITH AN ADDED DISULFIDE BETWEEN RESIDUES 5 AND 33 (L5C/H33C)

Gerber, N., Lowman, H., Artis, D.R., Eigenbrot, C.

(2000) Proteins 38: 361-367

Released	2000-03-22
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Homo sapiens
Macromolecule	INTERLEUKIN-8 VARIANT (protein)
Unique Ligands	SO4

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1T9R \| pdb_00001t9r	Download File View File

Catalytic Domain Of Human Phosphodiesterase 5A

Zhang, K.Y.J., Card, G.L., Suzuki, Y., Artis, D.R., Fong, D., Gillette, S., Hsieh, D., Neiman, J., West, B.L., Zhang, C., Milburn, M.V., Kim, S.-H., Schlessinger, J., Bollag, G.

(2004) Mol Cell 15: 279-286

Released	2004-08-03
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	cGMP-specific 3',5'-cyclic phosphodiesterase (protein)
Unique Ligands	CIT, PO4, ZN

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1T9S \| pdb_00001t9s	Download File View File

Catalytic Domain Of Human Phosphodiesterase 5A in Complex with GMP

Zhang, K.Y.J., Card, G.L., Suzuki, Y., Artis, D.R., Fong, D., Gillette, S., Hsieh, D., Neiman, J., West, B.L., Zhang, C., Milburn, M.V., Kim, S.-H., Schlessinger, J., Bollag, G.

(2004) Mol Cell 15: 279-286

Released	2004-08-03
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	cGMP-specific 3',5'-cyclic phosphodiesterase (protein)
Unique Ligands	5GP, MG, ZN

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1TAZ \| pdb_00001taz	Download File View File

Catalytic Domain Of Human Phosphodiesterase 1B

Zhang, K.Y.J., Card, G.L., Suzuki, Y., Artis, D.R., Fong, D., Gillette, S., Hsieh, D., Neiman, J., West, B.L., Zhang, C., Milburn, M.V., Kim, S.-H., Schlessinger, J., Bollag, G.

(2004) Mol Cell 15: 279-286

Released	2004-08-03
Method	X-RAY DIFFRACTION 1.77 Å
Organisms	Homo sapiens
Macromolecule	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (protein)
Unique Ligands	MG, ZN

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1TB5 \| pdb_00001tb5	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With AMP

Zhang, K.Y.J., Card, G.L., Suzuki, Y., Artis, D.R., Fong, D., Gillette, S., Hsieh, D., Neiman, J., West, B.L., Zhang, C., Milburn, M.V., Kim, S.-H., Schlessinger, J., Bollag, G.

(2004) Mol Cell 15: 279-286

Released	2004-08-03
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	AMP, MG, ZN

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1TB7 \| pdb_00001tb7	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4D In Complex With AMP

Zhang, K.Y.J., Card, G.L., Suzuki, Y., Artis, D.R., Fong, D., Gillette, S., Hsieh, D., Neiman, J., West, B.L., Zhang, C., Milburn, M.V., Kim, S.-H., Schlessinger, J., Bollag, G.

(2004) Mol Cell 15: 279-286

Released	2004-08-03
Method	X-RAY DIFFRACTION 1.63 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (protein)
Unique Ligands	AMP, B3P, EDO, MG, ZN

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1TBB \| pdb_00001tbb	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Rolipram

Zhang, K.Y.J., Card, G.L., Suzuki, Y., Artis, D.R., Fong, D., Gillette, S., Hsieh, D., Neiman, J., West, B.L., Zhang, C., Milburn, M.V., Kim, S.-H., Schlessinger, J., Bollag, G.

(2004) Mol Cell 15: 279-286

Released	2004-08-03
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (protein)
Unique Ligands	EDO, MG, ROL, ZN

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1TBF \| pdb_00001tbf	Download File View File

Catalytic Domain Of Human Phosphodiesterase 5A in Complex with Sildenafil

Zhang, K.Y.J., Card, G.L., Suzuki, Y., Artis, D.R., Fong, D., Gillette, S., Hsieh, D., Neiman, J., West, B.L., Zhang, C., Milburn, M.V., Kim, S.-H., Schlessinger, J., Bollag, G.

(2004) Mol Cell 15: 279-286

Released	2004-08-03
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Homo sapiens
Macromolecule	cGMP-specific 3',5'-cyclic phosphodiesterase (protein)
Unique Ligands	GOL, MG, VIA, ZN

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1XLX \| pdb_00001xlx	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Cilomilast

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 2.19 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	CIO, MG, ZN

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1XLZ \| pdb_00001xlz	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Filaminast

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	FIL, MG, ZN

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1XM4 \| pdb_00001xm4	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Piclamilast

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	MG, PIL, ZN

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1XM6 \| pdb_00001xm6	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R)-Mesopram

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	5RM, MG, ZN

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1XMU \| pdb_00001xmu	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Roflumilast

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	MG, ROF, ZN

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1XMY \| pdb_00001xmy	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R)-Rolipram

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	MG, ROL, ZN

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1XN0 \| pdb_00001xn0	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R,S)-Rolipram

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	MG, ROL, ZN

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1XOM \| pdb_00001xom	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Cilomilast

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 1.55 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (protein)
Unique Ligands	CIO, EDO, MG, ZN

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1XON \| pdb_00001xon	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Piclamilast

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 1.72 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (protein)
Unique Ligands	B3P, EDO, MG, PIL, ZN

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1XOQ \| pdb_00001xoq	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Roflumilast

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 1.83 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (protein)
Unique Ligands	EDO, MG, ROF, ZN

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1XOR \| pdb_00001xor	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Zardaverine

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 1.54 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (protein)
Unique Ligands	MG, ZAR, ZN

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1XOS \| pdb_00001xos	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Sildenafil

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 2.28 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	MG, SO4, VIA, ZN

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1XOT \| pdb_00001xot	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Vardenafil

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 2.34 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (protein)
Unique Ligands	MG, VDN, ZN

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1XOZ \| pdb_00001xoz	Download File View File

Catalytic Domain Of Human Phosphodiesterase 5A In Complex With Tadalafil

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 1.37 Å
Organisms	Homo sapiens
Macromolecule	cGMP-specific 3',5'-cyclic phosphodiesterase (protein)
Unique Ligands	CIA, MG, ZN

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1XP0 \| pdb_00001xp0	Download File View File

Catalytic Domain Of Human Phosphodiesterase 5A In Complex With Vardenafil

Card, G.L., England, B.P., Suzuki, Y., Fong, D., Powell, B., Lee, B., Luu, C., Tabrizizad, M., Gillette, S., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2004) Structure 12: 2233-2247

Released	2004-12-14
Method	X-RAY DIFFRACTION 1.79 Å
Organisms	Homo sapiens
Macromolecule	cGMP-specific 3',5'-cyclic phosphodiesterase (protein)
Unique Ligands	MG, VDN, ZN

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1Y2B \| pdb_00001y2b	Download File View File

Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester

Card, G.L., Blasdel, L., England, B.P., Zhang, C., Suzuki, Y., Gillette, S., Fong, D., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.

(2005) Nat Biotechnol 23: 201-207

Released	2005-03-01
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Homo sapiens
Macromolecule	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (protein)
Unique Ligands	DEE, EDO, MG, ZN

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Refinement Resolution (Å)

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Enzyme Classification Name

Symmetry Type

SCOP Classification

1ICW | pdb_00001icw

1QE6 | pdb_00001qe6

1T9R | pdb_00001t9r

1T9S | pdb_00001t9s

1TAZ | pdb_00001taz

1TB5 | pdb_00001tb5

1TB7 | pdb_00001tb7

1TBB | pdb_00001tbb

1TBF | pdb_00001tbf

1XLX | pdb_00001xlx

1XLZ | pdb_00001xlz

1XM4 | pdb_00001xm4

1XM6 | pdb_00001xm6

1XMU | pdb_00001xmu

1XMY | pdb_00001xmy

1XN0 | pdb_00001xn0

1XOM | pdb_00001xom

1XON | pdb_00001xon

1XOQ | pdb_00001xoq

1XOR | pdb_00001xor

1XOS | pdb_00001xos

1XOT | pdb_00001xot

1XOZ | pdb_00001xoz

1XP0 | pdb_00001xp0

1Y2B | pdb_00001y2b