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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Lambert, J.P."

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Search Summary

This query matches 23 Structures.

Refinements

Structure Determination Methodology

experimental (23)

Scientific Name of Source Organism

	Pyricularia grisea (10)
	Homo sapiens (6)
	Rattus norvegicus (3)
	Streptococcus pneumoniae R6 (2)
	Escherichia coli K-12 (1)
	Escherichia coli str. K-12 substr. MG1655 (1)
	Helicobacter pylori (1)
	Thermus thermophilus HB8 (1)

Taxonomy

	Eukaryota (19)
	Bacteria (4)

Experimental Method

X-RAY DIFFRACTION (23)

Polymer Entity Type

	Protein (23)
	RNA (1)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (12)
	2.0 - 2.5 (8)
	2.5 - 3.0 (1)
	3.0 - 3.5 (1)

Release Date

	1995 - 1999 (9)
	2000 - 2004 (4)
	2010 - 2014 (4)
	2020 - 2024 (6)

Enzyme Classification Name

	Hydrolases (6)
	Lyases (7)
	Isomerases (3)
	Oxidoreductases (3)

Symmetry Type

	Cyclic (11)
	Asymmetric (9)
	Dihedral (3)
	Tetrahedral (1)

SCOP Classification

	Alpha and beta proteins (a+b) (12)
	Artifacts (4)
	Alpha and beta proteins (a/b) (3)

AllSelected

1 to 23 of 23 Structures

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1AR0 \| pdb_00001ar0	Download File View File

NUCLEAR TRANSPORT FACTOR 2 (NTF2) E42K MUTANT

Mccoy, A.J., Stewart, M.J.

(1997) J Mol Biology 272: 716-730

Released	1997-12-24
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Rattus norvegicus
Macromolecule	NUCLEAR TRANSPORT FACTOR 2 (protein)

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1ASK \| pdb_00001ask	Download File View File

NUCLEAR TRANSPORT FACTOR 2 (NTF2) H66A MUTANT

Mccoy, A.J., Stewart, M.J.

(1997) J Mol Biology 272: 716-730

Released	1998-01-28
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Rattus norvegicus
Macromolecule	NUCLEAR TRANSPORT FACTOR 2 (protein)

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1DOH \| pdb_00001doh	Download File View File

STRUCTURE OF TRIHYDROXYNAPHTHALENE REDUCTASE IN COMPLEX WITH NADPH AND 4-NITRO-INDEN-1-ONE

Liao, D.I., Basarab, G.S., Gatenby, A.A., Jordan, D.B.

(2001) Structure 9: 19-28

Released	2001-06-06
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Pyricularia grisea
Macromolecule	TRIHYDROXYNAPHTHALENE REDUCTASE (protein)
Unique Ligands	NDP, NID

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1G0N \| pdb_00001g0n	Download File View File

STRUCTURE OF TRIHYDROXYNAPHTHALENE REDUCTASE IN COMPLEX WITH NADPH AND 4,5,6,7-TETRACHLORO-PHTHALIDE

Liao, D., Basarab, G.S., Gatenby, A.A., Valent, B., Jordan, D.B.

(2001) Structure 9: 19-28

Released	2001-06-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Pyricularia grisea
Macromolecule	TRIHYDROXYNAPHTHALENE REDUCTASE (protein)
Unique Ligands	NDP, PHH

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1G0O \| pdb_00001g0o	Download File View File

STRUCTURE OF TRIHYDROXYNAPHTHALENE REDUCTASE IN COMPLEX WITH NADPH AND PYROQUILON

Liao, D., Basarab, G.S., Gatenby, A.A., Valent, B., Jordan, D.B.

(2001) Structure 9: 19-28

Released	2001-06-06
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Pyricularia grisea
Macromolecule	TRIHYDROXYNAPHTHALENE REDUCTASE (protein)
Unique Ligands	NDP, PYQ

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1IDP \| pdb_00001idp	Download File View File

Crystal structure of scytalone dehydratase F162A mutant in the unligated state

Nakasako, M., Motoyama, T., Yamaguchi, I.

(2002) Acta Crystallogr D Biol Crystallogr 58: 148-150

Released	2003-04-08
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Pyricularia grisea
Macromolecule	SCYTALONE DEHYDRATASE (protein)

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1OUN \| pdb_00001oun	Download File View File

CRYSTAL STRUCTURE OF NUCLEAR TRANSPORT FACTOR 2 (NTF2)

Bullock, T.L., Stewart, M.J.

(1996) J Mol Biology 260: 422-431

Released	1997-04-01
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Rattus norvegicus
Macromolecule	NUCLEAR TRANSPORT FACTOR 2 (protein)

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1STD \| pdb_00001std	Download File View File

CRYSTAL STRUCTURE OF SCYTALONE DEHYDRATASE: A DISEASE DETERMINANT OF THE RICE PATHOGEN, MAGNAPORTHE GRISEA

Lundqvist, T., Lindqvist, Y.

(1994) Structure 2: 937-944

Released	1995-08-19
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Pyricularia grisea
Macromolecule	SCYTALONE DEHYDRATASE (protein)
Unique Ligands	BFS, SO4

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3STD \| pdb_00003std	Download File View File

SCYTALONE DEHYDRATASE AND CYANOCINNOLINE INHIBITOR

Chen, J.M., Xu, S.L., Wawrzak, Z., Basarab, G.S., Jordan, D.B.

(1998) Biochemistry 37: 17735-17744

Released	1999-10-16
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Pyricularia grisea
Macromolecule	PROTEIN (SCYTALONE DEHYDRATASE) (protein)
Unique Ligands	CA, MQ0

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4B1F \| pdb_00004b1f	Download File View File

Design of Inhibitors of Helicobacter pylori Glutamate Racemase as Selective Antibacterial Agents: Incorporation of Imidazoles onto a Core Pyrazolopyrimidinedione Scaffold to Improve Bioavailabilty

Basarab, G.S., Hill, P., Eyermann, C.J., Gowravaram, M., Kack, H., Osimoni, E.

(2012) Bioorg Med Chem Lett 22: 5600

Released	2012-07-18
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Helicobacter pylori
Macromolecule	GLUTAMATE RACEMASE (protein)
Unique Ligands	DGL, KRH

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4LP0 \| pdb_00004lp0	Download File View File

Crystal structure of a topoisomerase ATP inhibitor

Basarab, G.S., Manchester, J.I., Bist, S., Boriack-Sjodin, P.A., Dangel, B., Illingsworth, R., Uria-Nickelsen, M., Sherer, B.A., Sriram, S., Eakin, A.E.

(2013) J Med Chem 56: 8712-8735

Released	2013-11-13
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	Topoisomerase IV subunit B (protein)
Unique Ligands	1YM

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4LPB \| pdb_00004lpb	Download File View File

Crystal structure of a topoisomerase ATPase inhibitor

Boriack-Sjodin, A.

(2013) J Med Chem 56: 8712-8735

Released	2013-10-30
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	Topoisomerase IV subunit B (protein)
Unique Ligands	1YP

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4STD \| pdb_00004std	Download File View File

HIGH RESOLUTION STRUCTURES OF SCYTALONE DEHYDRATASE-INHIBITOR COMPLEXES CRYSTALLIZED AT PHYSIOLOGICAL PH

Wawrzak, Z., Sandalova, T., Steffens, J.J., Basarab, G.S., Lundqvist, T., Lindqvist, Y., Jordan, D.B.

(1999) Proteins 35: 425-439

Released	1999-12-29
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Pyricularia grisea
Macromolecule	Scytalone dehydratase (protein)
Unique Ligands	BFS

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4WF1 \| pdb_00004wf1	Download File View File

Crystal structure of the E. coli ribosome bound to negamycin.

Olivier, N.B., Altman, R.B., Noeske, J., Basarab, G.S., Code, E., Ferguson, A.D., Gao, N., Huang, J., Juette, M.F., Livchak, S., Miller, M.D., Prince, D.B., Cate, J.H.D., Buurman, E.T., Blanchard, S.C.

(2014) Proc Natl Acad Sci U S A 111: 16274-16279

Released	2014-11-05
Method	X-RAY DIFFRACTION 3.09 Å
Organisms	Escherichia coli K-12 Escherichia coli str. K-12 substr. MG1655 Thermus thermophilus HB8
Macromolecule	Unique protein chains: 50 Unique nucleic acid chains: 3
Unique Ligands	MG, NEG, ZN

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5STD \| pdb_00005std	Download File View File

SCYTALONE DEHYDRATASE PLUS INHIBITOR 2

Wawrzak, Z., Sandalova, T., Steffens, J.J., Basarab, G.S., Lundqvist, T., Lindqvist, Y., Jordan, D.B.

(1999) Proteins 35: 425-439

Released	1999-12-29
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Pyricularia grisea
Macromolecule	Scytalone dehydratase (protein)
Unique Ligands	CA, UNN

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6STD \| pdb_00006std	Download File View File

SCYTALONE DEHYDRATASE PLUS INHIBITOR 3

Wawrzak, Z., Sandalova, T., Steffens, J.J., Basarab, G.S., Lundqvist, T., Lindqvist, Y., Jordan, D.B.

(1999) Proteins 35: 425-439

Released	1999-12-29
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Pyricularia grisea
Macromolecule	Scytalone dehydratase (protein)
Unique Ligands	CA, MS2

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7Q24 \| pdb_00007q24	Download File View File

Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with dual ACE/NEP inhibitor AD011

Cozier, G.E., Acharya, K.R.

(2022) J Med Chem 65: 3371-3387

Released	2022-02-16
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Angiotensin-converting enzyme (protein)
Unique Ligands	8KC, ACT, CL, EDO, MG, NAG, P33, P6G, PEG, PG4, ZN
Unique branched monosaccharides	BMA, FUC, NAG

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7Q25 \| pdb_00007q25	Download File View File

Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with dual ACE/NEP inhibitor AD012

Cozier, G.E., Acharya, K.R.

(2022) J Med Chem 65: 3371-3387

Released	2022-02-16
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	Angiotensin-converting enzyme (protein)
Unique Ligands	1PE, 8J9, ACT, CL, EDO, MG, NAG, P33, PEG, PG4, ZN
Unique branched monosaccharides	BMA, FUC, NAG

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7Q26 \| pdb_00007q26	Download File View File

Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with dual ACE/NEP inhibitor AD013

Cozier, G.E., Acharya, K.R.

(2022) J Med Chem 65: 3371-3387

Released	2022-02-16
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Angiotensin-converting enzyme (protein)
Unique Ligands	1PE, 8JV, ACT, CL, EDO, MG, NAG, PE8, PEG, PG4, PGE, ZN
Unique branched monosaccharides	BMA, FUC, NAG

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7Q27 \| pdb_00007q27	Download File View File

Crystal structure of Angiotensin-1 converting enzyme C-domain in complex with dual ACE/NEP inhibitor AD011

Cozier, G.E., Acharya, K.R.

(2022) J Med Chem 65: 3371-3387

Released	2022-02-16
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	Angiotensin-converting enzyme (protein)
Unique Ligands	1PE, 8KC, ACT, BO3, CL, EDO, IMD, NAG, ZN
Unique branched monosaccharides	BMA, FUC, NAG

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7Q28 \| pdb_00007q28	Download File View File

Crystal structure of Angiotensin-1 converting enzyme C-domain in complex with dual ACE/NEP inhibitor AD012

Cozier, G.E., Acharya, K.R.

(2022) J Med Chem 65: 3371-3387

Released	2022-02-16
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	Angiotensin-converting enzyme (protein)
Unique Ligands	8J9, BO3, CL, EDO, NAG, PEG, ZN
Unique branched monosaccharides	BMA, FUC, MAN, NAG

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7Q29 \| pdb_00007q29	Download File View File

Crystal structure of Angiotensin-1 converting enzyme C-domain in complex with dual ACE/NEP inhibitor AD013

Cozier, G.E., Acharya, K.R.

(2022) J Med Chem 65: 3371-3387

Released	2022-02-16
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	Angiotensin-converting enzyme (protein)
Unique Ligands	1PE, 8JV, BO3, CL, EDO, IMD, NAG, PEG, ZN
Unique branched monosaccharides	BMA, FUC, MAN, NAG