RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Citation Author = "McGee, L.R."

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 49 Structures.

Refinements

Structure Determination Methodology

experimental (49)

Scientific Name of Source Organism

	Homo sapiens (47)
	Influenza A virus (3)
	Influenza B virus (2)
	Lama glama (1)
	Mus musculus (1)
	Rattus norvegicus (1)
	Severe acute respiratory syndrome coronavirus 2 (1)
	unidentified influenza virus (1)

Taxonomy

	Eukaryota (49)
	Riboviria (7)

Experimental Method

	X-RAY DIFFRACTION (48)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (49)

Refinement Resolution (Å)

	1.0 - 1.5 (3)
	1.5 - 2.0 (19)
	2.0 - 2.5 (16)
	2.5 - 3.0 (8)
	3.0 - 3.5 (2)

Release Date

	2005 - 2009 (8)
	2010 - 2014 (13)
	2015 - 2019 (17)
	2020 - 2024 (11)

Enzyme Classification Name

	Transferases (21)
	Hydrolases (8)

Symmetry Type

	Asymmetric (49)
	Cyclic (9)

SCOP Classification

	All beta proteins (12)
	Alpha and beta proteins (a+b) (14)
	Membrane and cell surface proteins and peptides (13)
	All alpha proteins (4)
	Alpha and beta proteins (a/b) (1)
	Artifacts (3)

AllSelected

1 to 25 of 49 Structures

Page 1 of 2

Sort by

Explore in 3D

2OU7 \| pdb_00002ou7	Download File View File

Structure of the Catalytic Domain of Human Polo-like Kinase 1

Ding, Y.-H., Kothe, M., Kohls, D., Low, S.

(2007) Biochemistry 46: 5960-5971

Released	2007-04-24
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase PLK1 (protein)
Unique Ligands	ACT, ANP, MG, ZN

Explore in 3D

2OWB \| pdb_00002owb	Download File View File

Structure of the Catalytic Domain of Human Polo-like Kinase 1

Ding, Y.-H., Kothe, M., Kohls, D., Low, S.

(2007) Biochemistry 46: 5960-5971

Released	2007-04-24
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase PLK1 (protein)
Unique Ligands	626, ACT, ZN

Explore in 3D

3B2W \| pdb_00003b2w	Download File View File

Crystal structure of pyrimidine amide 11 bound to Lck

Huang, X.

(2008) Bioorg Med Chem Lett 18: 1172-1176

Released	2007-12-18
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Proto-oncogene tyrosine-protein kinase LCK (protein)
Unique Ligands	9NH

Explore in 3D

3DA6 \| pdb_00003da6	Download File View File

Crystal Structure of human JNK3 complexed with N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine

Cee, V.J., Cheng, A.C., Romero, K., Bellon, S., Mohr, C., Whittington, D.A., Bready, J., Caenepeel, S., Coxon, A., Deak, H.L., Hodous, B.L., Kim, J.L., Lin, J., Nguyen, H., Olivieri, P.R., Patel, V.F., Wang, L., Hughes, P., Geuns-Meyer, S.

(2009) Bioorg Med Chem Lett 19: 424-427

Released	2009-01-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase 10 (protein)
Unique Ligands	BZ9

Explore in 3D

3EFW \| pdb_00003efw	Download File View File

Structure of AuroraA with pyridyl-pyrimidine urea inhibitor

Bellon, S.F., Cee, V., Hughes, P., Geuns-Meyer, S., Whittington, D.

(2009) Bioorg Med Chem Lett 19: 424-427

Released	2008-12-23
Method	X-RAY DIFFRACTION 2.29 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase 6 (protein)
Unique Ligands	AK8, SO4

Explore in 3D

3EWH \| pdb_00003ewh	Download File View File

Crystal structure of the VEGFR2 kinase domain in complex with a pyridyl-pyrimidine benzimidazole inhibitor

Whittington, D.A., Long, A.M., Rose, P., Gu, Y., Zhao, H.

(2009) Bioorg Med Chem Lett 19: 424-427

Released	2009-08-25
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	vascular endothelial growth factor receptor 2 (protein)
Unique Ligands	EDO, K11

Explore in 3D

3K3I \| pdb_00003k3i	Download File View File

p38alpha bound to novel DGF-out compound PF-00215955

Kazmirski, S.L., DiNitto, J.P.

(2009) Chem Biol Drug Des 74: 547-559

Released	2009-11-17
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase 14 (protein)
Unique Ligands	I46, JZJ

Explore in 3D

3K3J \| pdb_00003k3j	Download File View File

P38alpha bound to novel DFG-out compound PF-00416121

Kazmirski, S.L., DiNitto, J.P.

(2009) Chem Biol Drug Des 74: 547-559

Released	2009-11-10
Method	X-RAY DIFFRACTION 1.995 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase 14 (protein)
Unique Ligands	F4C, I46

Explore in 3D

3O50 \| pdb_00003o50	Download File View File

Crystal structure of benzamide 9 bound to AuroraA

Huang, X.

(2010) J Med Chem 53: 6368-6377

Released	2010-08-18
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	cDNA FLJ58295, highly similar to Serine/threonine-protein kinase 6 (protein)
Unique Ligands	LJE

Explore in 3D

3O51 \| pdb_00003o51	Download File View File

Crystal structure of anthranilamide 10 bound to AuroraA

Huang, X.

(2010) J Med Chem 53: 6368-6377

Released	2010-08-18
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens
Macromolecule	cDNA FLJ58295, highly similar to Serine/threonine-protein kinase 6 (protein)
Unique Ligands	LJF

Explore in 3D

3QAQ \| pdb_00003qaq	Download File View File

Crystal structure of PI3K-gamma in complex with triazine-benzimidazole 1

Whittington, D.A., Tang, J., Yakowec, P.

(2011) Bioorg Med Chem Lett 21: 2064-2070

Released	2011-03-30
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (protein)
Unique Ligands	QAQ, SO4

Explore in 3D

3QAR \| pdb_00003qar	Download File View File

Crystal structure of PI3K-gamma in complex with triazine-benzimidazole 32

Whittington, D.A., Tang, J., Yakowec, P.

(2011) Bioorg Med Chem Lett 21: 2064-2070

Released	2011-03-30
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Homo sapiens
Macromolecule	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (protein)
Unique Ligands	QAR, SO4

Explore in 3D

4DCE \| pdb_00004dce	Download File View File

Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor

Whittington, D.A., Epstein, L.F., Chen, H.

(2012) J Med Chem 55: 1698-1705

Released	2012-02-08
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Homo sapiens
Macromolecule	ALK tyrosine kinase receptor (protein)
Unique Ligands	0JF

Explore in 3D

4FHJ \| pdb_00004fhj	Download File View File

Crystal Structure of PI3K-gamma in Complex with Imidazopyridine 2

Shaffer, P.L., Tang, J., Yakowec, P.

(2012) Bioorg Med Chem Lett 22: 4967-4974

Released	2012-07-18
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (protein)
Unique Ligands	0TZ, SO4

Explore in 3D

4FHK \| pdb_00004fhk	Download File View File

Crystal Structure of PI3K-gamma in Complex with Imidazopyridazine 19e

Shaffer, P.L., Tang, J., Yakowec, P.

(2012) Bioorg Med Chem Lett 22: 4967-4974

Released	2013-04-10
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (protein)
Unique Ligands	0U0, SO4

Explore in 3D

4FRI \| pdb_00004fri	Download File View File

Crystal structure of BACE1 in complex with biarylspiro aminooxazoline 6

Whittington, D.A., Long, A.M.

(2012) J Med Chem 55: 9156-9169

Released	2012-09-12
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Beta-secretase 1 (protein)
Unique Ligands	DMS, DWA, IOD

Explore in 3D

4FRJ \| pdb_00004frj	Download File View File

Crystal structure of BACE1 in complex with aminooxazoline xanthene 9l

Whittington, D.A., Long, A.M.

(2012) J Med Chem 55: 9156-9169

Released	2012-09-12
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	Beta-secretase 1 (protein)
Unique Ligands	DMS, DWB, GOL, IOD

Explore in 3D

4FRK \| pdb_00004frk	Download File View File

Crystal structure of BACE1 in complex with aminooxazoline xanthene 11a

Whittington, D.A., Long, A.M.

(2012) J Med Chem 55: 9156-9169

Released	2012-09-12
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Beta-secretase 1 (protein)
Unique Ligands	DWD, GOL, IOD

Explore in 3D

4L02 \| pdb_00004l02	Download File View File

Crystal Structure of SphK1 with inhibitor

Min, X., Walker, N., Wang, Z.

(2013) Bioorg Med Chem Lett 23: 4608-4616

Released	2013-07-24
Method	X-RAY DIFFRACTION 2.75 Å
Organisms	Homo sapiens
Macromolecule	Sphingosine kinase 1 (protein)
Unique Ligands	1V2

Explore in 3D

4RCD \| pdb_00004rcd	Download File View File

Crystal structure of BACE1 in complex with a 2-aminooxazoline 4-azaxanthene inhibitor

Whittington, D.A., Long, A.M.

(2014) J Med Chem 57: 9811-9831

Released	2015-01-21
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Beta-secretase 1 (protein)
Unique Ligands	3LL, GOL, IOD

Explore in 3D

4RCE \| pdb_00004rce	Download File View File

Crystal structure of BACE1 in complex with aminooxazoline xanthene inhibitor 2

Whittington, D.A., Long, A.M.

(2014) J Med Chem 57: 9796-9810

Released	2014-12-24
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Beta-secretase 1 (protein)
Unique Ligands	3LN, IOD

Explore in 3D

4RCF \| pdb_00004rcf	Download File View File

Crystal structure of BACE1 in complex with 2-aminooxazoline 4-fluoroxanthene inhibitor 49

Whittington, D.A., Long, A.M.

(2014) J Med Chem 57: 9796-9810

Released	2014-12-24
Method	X-RAY DIFFRACTION 1.78 Å
Organisms	Homo sapiens
Macromolecule	Beta-secretase 1 (protein)
Unique Ligands	3LO, GOL, IOD

Explore in 3D

4XKX \| pdb_00004xkx	Download File View File

Crystal structure of BACE1 in complex with 2-aminooxazoline 3-azaxanthene inhibitor 28

Whittington, D.A., Long, A.M.

(2015) Bioorg Med Chem Lett 25: 767-774

Released	2015-02-04
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Beta-secretase 1 (protein)
Unique Ligands	43K, GOL, IOD

Explore in 3D

5VTA \| pdb_00005vta	Download File View File

Co-Crystal Structure of DPPIV with a Chemibody Inhibitor

Wang, Z., Johnstone, S., Cheng, A.

(2018) Sci Rep 8: 7570-7570

Released	2018-05-09
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Mus musculus Rattus norvegicus
Macromolecule	Dipeptidyl peptidase 4 (protein) Fab heavy chain (protein) Fab light chain (protein)
Unique Ligands	9K4, EDO, NAG, PEG, PG4

Explore in 3D

6O6F \| pdb_00006o6f	Download File View File

Co-crystal structure of Mcl1 with inhibitor

Huang, X.

(2018) Cancer Discov 8: 1582-1597

Released	2019-05-15
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	Induced myeloid leukemia cell differentiation protein Mcl-1 (protein)
Unique Ligands	LOD

1 to 25 of 49 Structures

Page 1 of 2

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

2OU7 | pdb_00002ou7

2OWB | pdb_00002owb

3B2W | pdb_00003b2w

3DA6 | pdb_00003da6

3EFW | pdb_00003efw

3EWH | pdb_00003ewh

3K3I | pdb_00003k3i

3K3J | pdb_00003k3j

3O50 | pdb_00003o50

3O51 | pdb_00003o51

3QAQ | pdb_00003qaq

3QAR | pdb_00003qar

4DCE | pdb_00004dce

4FHJ | pdb_00004fhj

4FHK | pdb_00004fhk

4FRI | pdb_00004fri

4FRJ | pdb_00004frj

4FRK | pdb_00004frk

4L02 | pdb_00004l02

4RCD | pdb_00004rcd

4RCE | pdb_00004rce

4RCF | pdb_00004rcf

4XKX | pdb_00004xkx

5VTA | pdb_00005vta

6O6F | pdb_00006o6f