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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Moncrieffe, M.C."

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Search Summary

This query matches 13 Structures.

Refinements

Structure Determination Methodology

experimental (13)

Scientific Name of Source Organism

	Aedes aegypti (3)
	Escherichia coli (3)
	Homo sapiens (3)
	Drosophila melanogaster (1)
	Gallus gallus (1)
	Pseudomonas aeruginosa (1)
	Saccharopolyspora erythraea NRRL 2338 (1)

Taxonomy

	Eukaryota (8)
	Bacteria (5)

Experimental Method

	X-RAY DIFFRACTION (8)
	ELECTRON MICROSCOPY (4)
	SOLUTION NMR (1)

Polymer Entity Type

Protein (13)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (1)
	2.5 - 3.0 (2)
	3.0 - 3.5 (6)
	3.5 - 4.0 (1)
	4.0 - 4.5 (1)

Release Date

	2000 - 2004 (1)
	2005 - 2009 (1)
	2010 - 2014 (1)
	2015 - 2019 (5)
	2020 - 2024 (5)

Enzyme Classification Name

Transferases (2)

Symmetry Type

	Cyclic (7)
	Asymmetric (5)
	Helical (1)

SCOP Classification

	Alpha and beta proteins (a+b) (2)
	Artifacts (2)
	All alpha proteins (1)
	All beta proteins (1)

AllSelected

1 to 13 of 13 Structures

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1W2E \| pdb_00001w2e	Download File View File

The Crystal Structure of the Bacterial Cell Division Protein ZapA

Low, H.H., Moncrieffe, M.C., Lowe, J.

(2004) J Mol Biology 341: 839

Released	2004-07-19
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Pseudomonas aeruginosa
Macromolecule	ZAPA (protein)

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1YGO \| pdb_00001ygo	Download File View File

Solution Structure of the pelle Death Domain

Moncrieffe, M.C., Stott, K.M., Gay, N.J.

(2005) FEBS Lett 579: 3920-3926

Released	2005-07-26
Method	SOLUTION NMR
Organisms	Drosophila melanogaster
Macromolecule	Probable serine/threonine-protein kinase pelle (protein)

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2YJN \| pdb_00002yjn	Download File View File

Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII

Moncrieffe, M.C., Fernandez, M.J., Spiteller, D., Matsumura, H., Gay, N.J., Luisi, B.F., Leadlay, P.F.

(2012) J Mol Biology 415: 92

Released	2011-11-09
Method	X-RAY DIFFRACTION 3.091 Å
Organisms	Saccharopolyspora erythraea NRRL 2338
Macromolecule	DTDP-4-KETO-6-DEOXY-HEXOSE 3,4-ISOMERASE (protein) GLYCOSYLTRANSFERASE (protein)

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5FOR \| pdb_00005for	Download File View File

Cryptic TIR

Halabi, S., Gay, N.J., Moncrieffe, M.C.

(2017) J Biological Chem 292: 652-660

Released	2016-12-07
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHOINOSITIDE 3-KINASE ADAPTER PROTEIN 1 (protein)
Unique Ligands	1PE, I3C

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5O5O \| pdb_00005o5o	Download File View File

X-ray crystal structure of RapZ from Escherichia coli (P32 space group)

Gonzalez, G.M., Durica-Mitic, S., Hardwick, S.W., Moncrieffe, M., Resch, M., Neumann, P., Ficner, R., Gorke, B., Luisi, B.F.

(2017) Nucleic Acids Res 45: 10845-10860

Released	2017-08-30
Method	X-RAY DIFFRACTION 3.404 Å
Organisms	Escherichia coli
Macromolecule	RNase adapter protein RapZ (protein)
Unique Ligands	SO4

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5O5Q \| pdb_00005o5q	Download File View File

X-ray crystal structure of RapZ from Escherichia coli (P3221 space group)

Gonzalez, G.M., Durica-Mitic, S., Hardwick, S.W., Moncrieffe, M., Resch, M., Neumann, P., Ficner, R., Gorke, B., Luisi, B.F.

(2017) Nucleic Acids Res 45: 10845-10860

Released	2017-08-30
Method	X-RAY DIFFRACTION 3.25 Å
Organisms	Escherichia coli
Macromolecule	RNase adapter protein RapZ (protein)
Unique Ligands	SO4

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5O5S \| pdb_00005o5s	Download File View File

X-ray crystal structure of the RapZ C-terminal domain from Escherichia coli

Gonzalez, G.M., Durica-Mitic, S., Hardwick, S.W., Moncrieffe, M., Resch, M., Neumann, P., Ficner, R., Gorke, B., Luisi, B.F.

(2017) Nucleic Acids Res 45: 10845-10860

Released	2017-08-30
Method	X-RAY DIFFRACTION 1.17 Å
Organisms	Escherichia coli
Macromolecule	RNase adapter protein RapZ (protein)
Unique Ligands	MLI

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6I3N \| pdb_00006i3n	Download File View File

Helical MyD88 death domain filament

Moncrieffe, M.C., Bollschweiler, D., Penczek, P.A.P., Gay, N.J.

(2020) Structure 28: 281-289.e3

Released	2019-11-20
Method	ELECTRON MICROSCOPY 3.1 Å
Organisms	Homo sapiens
Macromolecule	Myeloid differentiation primary response protein MyD88 (protein)

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6SWS \| pdb_00006sws	Download File View File

The DBB dimerization domain of B-cell adaptor for PI3K (BCAP) is required for down regulation of inflammatory signalling through the Toll-like receptor pathway

Lauenstein, J.U., Scherm, M.J., Udgata, A., Moncrieffe, M.C., Fisher, D., Gay, N.J.

(2020) J Immunol 204: 2269-2276

Released	2020-02-19
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	Phosphoinositide 3-kinase adapter protein 1 (protein)

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6T3Y \| pdb_00006t3y	Download File View File

Improved High Resolution Structure of MHC Class II complex

Halabi, S., Moncrieffe, M.C., Kaufman, J.

(2021) PLoS Biol 19: e3001057-e3001057

Released	2020-11-25
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Gallus gallus
Macromolecule	MHC class II alpha chain (protein) MHC class II beta chain 2 (protein)
Unique Ligands	ACT, GOL

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7B1B \| pdb_00007b1b	Download File View File

Cryo-EM of Aedes Aegypti Toll5A dimer bound to Spz1C

Gangloff, M., Hardwick, S.W., Chirgadze, D.Y.

(2022) Nat Commun 13: 5110-5110

Released	2022-07-13
Method	ELECTRON MICROSCOPY 4.23 Å
Organisms	Aedes aegypti
Macromolecule	AAEL013433-PA (protein) Toll-like receptor (protein)
Unique Ligands	NAG
Unique branched monosaccharides	BMA, NAG

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7B1C \| pdb_00007b1c	Download File View File

Cryo-EM of Aedes Aegypti Toll5A trimer bound to Spz1C

Gangloff, M., Hardwick, S.W., Chirgadze, D.Y.

(2022) Nat Commun 13: 5110-5110

Released	2022-07-13
Method	ELECTRON MICROSCOPY 3.74 Å
Organisms	Aedes aegypti
Macromolecule	AAEL013433-PA (protein) Toll-like receptor (protein)
Unique Ligands	NAG
Unique branched monosaccharides	BMA, NAG

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7B1D \| pdb_00007b1d	Download File View File

Cryo-EM of Aedes Aegypti Toll5A

Gangloff, M., Hardwick, S.W., Chirgadze, D.Y.

(2022) Nat Commun 13: 5110-5110

Released	2022-07-13
Method	ELECTRON MICROSCOPY 3.41 Å
Organisms	Aedes aegypti
Macromolecule	Toll-like receptor (protein)
Unique Ligands	NAG
Unique branched monosaccharides	NAG

1 to 13 of 13 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1W2E | pdb_00001w2e

The Crystal Structure of the Bacterial Cell Division Protein ZapA

1YGO | pdb_00001ygo

Solution Structure of the pelle Death Domain

2YJN | pdb_00002yjn

Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII

5FOR | pdb_00005for

Cryptic TIR

5O5O | pdb_00005o5o

X-ray crystal structure of RapZ from Escherichia coli (P32 space group)

5O5Q | pdb_00005o5q

X-ray crystal structure of RapZ from Escherichia coli (P3221 space group)

5O5S | pdb_00005o5s

X-ray crystal structure of the RapZ C-terminal domain from Escherichia coli

6I3N | pdb_00006i3n

Helical MyD88 death domain filament

6SWS | pdb_00006sws

The DBB dimerization domain of B-cell adaptor for PI3K (BCAP) is required for down regulation of inflammatory signalling through the Toll-like receptor pathway

6T3Y | pdb_00006t3y

Improved High Resolution Structure of MHC Class II complex

7B1B | pdb_00007b1b

Cryo-EM of Aedes Aegypti Toll5A dimer bound to Spz1C

7B1C | pdb_00007b1c

Cryo-EM of Aedes Aegypti Toll5A trimer bound to Spz1C

7B1D | pdb_00007b1d

Cryo-EM of Aedes Aegypti Toll5A

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1W2E | pdb_00001w2e

1YGO | pdb_00001ygo

2YJN | pdb_00002yjn

5FOR | pdb_00005for

5O5O | pdb_00005o5o

5O5Q | pdb_00005o5q

5O5S | pdb_00005o5s

6I3N | pdb_00006i3n

6SWS | pdb_00006sws

6T3Y | pdb_00006t3y

7B1B | pdb_00007b1b

7B1C | pdb_00007b1c

7B1D | pdb_00007b1d