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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Page, L.W."

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Search Summary

This query matches 23 Structures.

Refinements

Structure Determination Methodology

experimental (23)

Scientific Name of Source Organism

Homo sapiens (23)

Taxonomy

Eukaryota (23)

Experimental Method

X-RAY DIFFRACTION (23)

Polymer Entity Type

Protein (23)

Refinement Resolution (Å)

	1.5 - 2.0 (3)
	2.0 - 2.5 (19)
	2.5 - 3.0 (1)

Release Date

2015 - 2019 (23)

Enzyme Classification Name

	Hydrolases (17)
	Transferases (6)

Symmetry Type

	Asymmetric (22)
	Cyclic (1)

SCOP Classification

	Alpha and beta proteins (a+b) (4)
	Artifacts (4)
	Small proteins (2)

AllSelected

1 to 23 of 23 Structures

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Explore in 3D

5BVK \| pdb_00005bvk	Download File View File

Fragment-based discovery of potent and selective DDR1/2 inhibitors

Murray, C., Berdini, V., Buck, I., Carr, M., Cleasby, A., Coyle, J., Curry, J., Day, J., Hearn, K., Iqbal, A., Lee, L., Martins, V., Mortenson, P., Munck, J., Page, L., Patel, S., Roomans, S., Kirsten, T., Saxty, G.

(2015) ACS Med Chem Lett 6: 798-803

Released	2015-08-05
Method	X-RAY DIFFRACTION 2.29 Å
Organisms	Homo sapiens
Macromolecule	Epithelial discoidin domain-containing receptor 1 (protein)
Unique Ligands	4VC, IOD

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5BVN \| pdb_00005bvn	Download File View File

Fragment-based discovery of potent and selective DDR1/2 inhibitors

(2015) ACS Med Chem Lett 6: 798-803

Released	2015-08-12
Method	X-RAY DIFFRACTION 2.21 Å
Organisms	Homo sapiens
Macromolecule	Epithelial discoidin domain-containing receptor 1 (protein)
Unique Ligands	4VD, IOD

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5BVO \| pdb_00005bvo	Download File View File

Fragment-based discovery of potent and selective DDR1/2 inhibitors

(2015) ACS Med Chem Lett 6: 798-803

Released	2015-08-05
Method	X-RAY DIFFRACTION 1.98 Å
Organisms	Homo sapiens
Macromolecule	Epithelial discoidin domain-containing receptor 1 (protein)
Unique Ligands	4VE, IOD

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5BVW \| pdb_00005bvw	Download File View File

Fragment-based discovery of potent and selective DDR1/2 inhibitors

(2015) ACS Med Chem Lett 6: 798-803

Released	2015-08-05
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Homo sapiens
Macromolecule	Epithelial discoidin domain-containing receptor 1 (protein)
Unique Ligands	1N1, IOD

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5JAD \| pdb_00005jad	Download File View File

Compound binding to Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)discovered through fragment screening

Day, P.J., Woolford, A.J.-A.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	CL, DMS, FB2, MG

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5JAH \| pdb_00005jah	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HQ, CL

Explore in 3D

5JAL \| pdb_00005jal	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HO, CL, DMS, MG

Explore in 3D

5JAN \| pdb_00005jan	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.12 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HP, CA, CL

Explore in 3D

5JAO \| pdb_00005jao	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HX, CA, CL, DMS

Explore in 3D

5JAP \| pdb_00005jap	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.46 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HZ, CA, CL, DMS

Explore in 3D

5JAR \| pdb_00005jar	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HV, CL, DMS

Explore in 3D

5JAS \| pdb_00005jas	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HW, CL, DMS

Explore in 3D

5JAT \| pdb_00005jat	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 2.04 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HR, CL, DMS

Explore in 3D

5JAU \| pdb_00005jau	Download File View File

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

Day, P.J.

(2016) J Med Chem 59: 5356-5367

Released	2016-05-25
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	6HU, CL, DMS

Explore in 3D

5LYY \| pdb_00005lyy	Download File View File

Fragment-based inhibitors of Lipoprotein associated Phospholipase A2

Woolford, A., Day, P.

(2016) J Med Chem 59: 10738-10749

Released	2016-12-21
Method	X-RAY DIFFRACTION 2.17 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	7BJ

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5LZ2 \| pdb_00005lz2	Download File View File

Fragment-based inhibitors of Lipoprotein associated Phospholipase A2

Woolford, A., Day, P.

(2016) J Med Chem 59: 10738-10749

Released	2016-12-21
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	7BX, CL, NA

Explore in 3D

5LZ4 \| pdb_00005lz4	Download File View File

Fragment-based inhibitors of Lipoprotein associated Phospholipase A2

Woolford, A., Day, P.

(2016) J Med Chem 59: 10738-10749

Released	2016-12-21
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	7BW, CL

Explore in 3D

5LZ5 \| pdb_00005lz5	Download File View File

Fragment-based inhibitors of Lipoprotein associated Phospholipase A2

Woolford, A.J.A., Day, P.J.

(2016) J Med Chem 59: 10738-10749

Released	2016-12-21
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	7K4, CL

Explore in 3D

5LZ7 \| pdb_00005lz7	Download File View File

Fragment-based inhibitors of Lipoprotein associated Phospholipase A2

Woolford, A., Day, P.

(2016) J Med Chem 59: 10738-10749

Released	2016-12-21
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	7BK, CL

Explore in 3D

5LZ8 \| pdb_00005lz8	Download File View File

Fragment-based inhibitors of Lipoprotein associated Phospholipase A2

Woolford, A., Day, P.

(2016) J Med Chem 59: 10738-10749

Released	2016-12-21
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	7BP, CL

Explore in 3D

5LZ9 \| pdb_00005lz9	Download File View File

Fragment-based inhibitors of Lipoprotein associated Phospholipase A2

Woolford, A., Day, P.

(2016) J Med Chem 59: 10738-10749

Released	2016-12-21
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Homo sapiens
Macromolecule	Platelet-activating factor acetylhydrolase (protein)
Unique Ligands	7BR, CL, NA

Explore in 3D

6H6Q \| pdb_00006h6q	Download File View File

Fragment Derived XIAP inhibitor

Williams, P.A.

(2018) J Med Chem 61: 7314-7329

Released	2018-08-22
Method	X-RAY DIFFRACTION 2.63 Å
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase XIAP (protein)
Unique Ligands	FUK, ZN

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6H6R \| pdb_00006h6r	Download File View File

Fragment Derived XIAP inhibitor

Williams, P.A.

(2018) J Med Chem 61: 7314-7329

Released	2018-08-22
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase XIAP (protein)
Unique Ligands	FUE, NA, ZN

1 to 23 of 23 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

5BVK | pdb_00005bvk

5BVN | pdb_00005bvn

5BVO | pdb_00005bvo

5BVW | pdb_00005bvw

5JAD | pdb_00005jad

5JAH | pdb_00005jah

5JAL | pdb_00005jal

5JAN | pdb_00005jan

5JAO | pdb_00005jao

5JAP | pdb_00005jap

5JAR | pdb_00005jar

5JAS | pdb_00005jas

5JAT | pdb_00005jat

5JAU | pdb_00005jau

5LYY | pdb_00005lyy

5LZ2 | pdb_00005lz2

5LZ4 | pdb_00005lz4

5LZ5 | pdb_00005lz5

5LZ7 | pdb_00005lz7

5LZ8 | pdb_00005lz8

5LZ9 | pdb_00005lz9

6H6Q | pdb_00006h6q

6H6R | pdb_00006h6r