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233,249 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "Vav1"

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Search Summary

This query matches 10 Structures.

Refinements

Structure Determination Methodology

experimental (10)

Scientific Name of Source Organism

	Homo sapiens (9)
	Mus musculus (3)
	Streptococcus sp. 'group G (1)

Taxonomy

	Eukaryota (10)
	Bacteria (1)
	Eukaryota (eukaryotes) (1)

Experimental Method

	SOLUTION NMR (5)
	X-RAY DIFFRACTION (5)

Polymer Entity Type

Protein (10)

Refinement Resolution (Å)

2.5 - 3.0 (5)

Release Date

	2005 - 2009 (4)
	2010 - 2014 (3)
	2015 - 2019 (3)

Enzyme Classification Name

	Transferases (2)
	Hydrolases (1)

Membrane Protein Annotation

OPM (1)

Symmetry Type

Asymmetric (10)

SCOP Classification

	Alpha and beta proteins (a/b) (1)
	Artifacts (1)
	Alpha and beta proteins (a+b) (1)

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1 to 10 of 10 Structures

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2CRH \| pdb_00002crh	Download File View File

Solution structure of the SH2 domain of human proto-oncogene protein VAV1

Endo, H., Hayashi, F., Yoshida, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

To be published

Released	2005-11-20
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Vav proto-oncogene (protein)

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2KBT \| pdb_00002kbt	Download File View File

Attachment of an NMR-invisible solubility enhancement tag (INSET) using a sortase-mediated protein ligation method

Kumeta, H., Kobashigawa, Y., Ogura, K., Inagaki, F.

(2009) J Biomol NMR 43: 145-150

Released	2009-02-03
Method	SOLUTION NMR
Organisms	Mus musculus Streptococcus sp. 'group G
Macromolecule	Proto-oncogene vav,Immunoglobulin G-binding protein G (protein)

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2LCT \| pdb_00002lct	Download File View File

Solution structure of the Vav1 SH2 domain complexed with a Syk-derived doubly phosphorylated peptide

Chen, C., Gorenstein, N., Post, C.

(2011) Mol Cell Biol 31: 2984-2996

Released	2011-06-01
Method	SOLUTION NMR
Organisms	Homo sapiens Mus musculus
Macromolecule	Proto-oncogene vav (protein) Tyrosine-protein kinase SYK (protein)

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2MC1 \| pdb_00002mc1	Download File View File

Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide

Chen, C., Piraner, D., Gorenstein, N.M., Geahlen, R.L., Post, C.B.

(2013) Biopolymers 99: 897-907

Released	2013-08-28
Method	SOLUTION NMR
Organisms	Homo sapiens Mus musculus
Macromolecule	Proto-oncogene vav (protein) Tyrosine-protein kinase SYK (protein)

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2ROR \| pdb_00002ror	Download File View File

Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76

Tanaka, M., Kasai, T., Koshiba, S., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

To be published

Released	2009-04-21
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	15-meric peptide from Lymphocyte cytosolic protein 2 (protein) Proto-oncogene vav (protein)

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3BJI \| pdb_00003bji	Download File View File

Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1

Chrencik, J.E., Brooun, A., Kuhn, P., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)

(2008) J Mol Biology 380: 828-843

Released	2008-07-15
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Proto-oncogene vav (protein) Ras-related C3 botulinum toxin substrate 1 precursor (protein)
Unique Ligands	ZN