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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 3.4.21.36

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Search Summary

This query matches 128 Structures.

Refinements

Structure Determination Methodology

experimental (128)

Scientific Name of Source Organism

	Sus scrofa (125)
	Homo sapiens (13)
	synthetic construct (3)
	Sus scrofa domesticus (2)
	Ascaris suum (1)
	Flexibacter sp. (1)
	Lyngbya (1)
	Salmo salar (1)
	Scytonema hofmannii (1)
	Stichodactyla helianthus (1)

More...

Taxonomy

	Eukaryota (128)
	Bacteria (4)
	other sequences (3)

Experimental Method

	X-RAY DIFFRACTION (128)
	NEUTRON DIFFRACTION (1)

Polymer Entity Type

Protein (128)

Refinement Resolution (Å)

	0.5 - 1.0 (3)
	1.0 - 1.5 (23)
	1.5 - 2.0 (77)
	2.0 - 2.5 (22)
	2.5 - 3.0 (3)
	3.0 - 3.5 (1)

Release Date

	1975 - 1979 (1)
	1985 - 1989 (2)
	1990 - 1994 (13)
	1995 - 1999 (18)
	2000 - 2004 (26)
	2005 - 2009 (38)
	2010 - 2014 (18)
	2015 - 2019 (2)
	2020 - 2024 (10)

Enzyme Classification Name

Hydrolases (128)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (128)
	Cyclic (1)

SCOP Classification

	All beta proteins (123)
	Small proteins (4)
	Multi-domain proteins (alpha and beta) (1)

AllSelected

1 to 25 of 128 Structures

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Explore in 3D

1B0E \| pdb_00001b0e	Download File View File

CRYSTAL STRUCTURE OF PORCINE PANCREATIC ELASTASE WITH MDL 101,146

Schreuder, H.A., Metz, W.A., Peet, N.P., Pelton, J.T., Tardif, C.

(1998) J Med Chem 41: 2461-2480

Released	1998-11-18
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Sus scrofa
Macromolecule	PROTEIN (ELASTASE) (protein)
Unique Ligands	CA, SEI

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1BMA \| pdb_00001bma	Download File View File

BENZYL METHYL AMINIMIDE INHIBITOR COMPLEXED TO PORCINE PANCREATIC ELASTASE

Peisach, E., Casebier, D., Gallion, S.L., Furth, P., Petsko, G.A., Hogan Jr., J.C., Ringe, D.

(1995) Science 269: 66-69

Released	1995-12-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Sus scrofa
Macromolecule	Chymotrypsin-like elastase family member 1 (protein)
Unique Ligands	0QH, CA, SO4

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1BTU \| pdb_00001btu	Download File View File

PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4R)-1-TOLUENESULPHONYL-3-ETHYL-AZETIDIN-2-ONE-4-CARBOXYLIC ACID

Wilmouth, R.C., Clifton, I.J., Schofield, C.J.

(1998) Biochemistry 37: 17506-17513

Released	1999-02-16
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	2BL, CA, SO4

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1C1M \| pdb_00001c1m	Download File View File

PORCINE ELASTASE UNDER XENON PRESSURE (8 BAR)

Prange, T., Schiltz, M., Pernot, L., Colloc'h, N., Longhi, S., Bourguet, W., Fourme, R.

(1998) Proteins 30: 61-73

Released	1999-07-28
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Sus scrofa
Macromolecule	PROTEIN (PORCINE ELASTASE) (protein)
Unique Ligands	CA, SO4, XE

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1E34 \| pdb_00001e34	Download File View File

PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA- TOLUENESULPHONYL-3-ETHYL-4-(CARBOXYLIC ACID) PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR ONE MINUTE

Wright, P.A., Wilmouth, R.C., Clifton, I.J., Schofield, C.J.

(2000) Biochem J 351: 335

Released	2000-10-18
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	CA, SO4, TPX

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1E35 \| pdb_00001e35	Download File View File

PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-TOLUENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR TWO MINUTES

Wright, P.A., Wilmouth, R.C., Clifton, I.J., Schofield, C.J.

(2000) Biochem J 351: 335

Released	2000-10-18
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	CA, SO4, TPX

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1E36 \| pdb_00001e36	Download File View File

PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-NITROBENZENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE

Wright, P.A., Wilmouth, R.C., Clifton, I.J., Schofield, C.J.

(2000) Biochem J 351: 335

Released	2000-10-18
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	CA, SO4, TPY

Explore in 3D

1E37 \| pdb_00001e37	Download File View File

PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-NITROBENZENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR 1 MINUTE

Wright, P.A., Wilmouth, R.C., Clifton, I.J., Schofield, C.J.

(2000) Biochem J 351: 335

Released	2000-10-18
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	CA, SO4, TPY

Explore in 3D

1E38 \| pdb_00001e38	Download File View File

PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-NITROBENZENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR 2 MINUTES

Wright, P.A., Wilmouth, R.C., Clifton, I.J., Schofield, C.J.

(2000) Biochem J 351: 335

Released	2000-10-18
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	CA, SO4, TPY

Explore in 3D

1EAI \| pdb_00001eai	Download File View File

COMPLEX OF ASCARIS CHYMOTRPSIN/ELASTASE INHIBITOR WITH PORCINE ELASTASE

Huang, K., Strynadka, N.C.J., Bernard, V.D., Peanasky, R.J., James, M.N.G.

(1994) Structure 2: 679-689

Released	1999-04-05
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Ascaris suum Sus scrofa
Macromolecule	PROTEIN (CHYMOTRYPSIN/ELASTASE ISOINHIBITOR 1) (protein) PROTEIN (ELASTASE) (protein)

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1EAS \| pdb_00001eas	Download File View File

NONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 3. DESIGN, SYNTHESIS, X-RAY CRYSTALLOGRAPHIC ANALYSIS, AND STRUCTURE-ACTIVITY RELATIONSHIPS FOR A SERIES OF ORALLY ACTIVE 3-AMINO-6-PHENYLPYRIDIN-2-ONE TRIFLUOROMETHYL KETONES

Ceccarelli, C.

(1994) J Med Chem 37: 3313-3326

Released	1995-02-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Sus scrofa
Macromolecule	PORCINE PANCREATIC ELASTASE (protein)
Unique Ligands	NA, SO4, TFK

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1EAT \| pdb_00001eat	Download File View File

NONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 5. DESIGN, SYNTHESIS, AND X-RAY CRYSTALLOGRAPHY OF A SERIES OF ORALLY ACTIVE 5-AMINO-PYRIMIDIN-6-ONE-CONTAINING TRIFLUOROMETHYLKETONES

Ceccarelli, C.

(1995) J Med Chem 38: 98-108

Released	1995-02-07
Method	X-RAY DIFFRACTION 2 Å
Organisms	Sus scrofa
Macromolecule	PORCINE PANCREATIC ELASTASE (protein)
Unique Ligands	NA, SO4, TFI

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1EAU \| pdb_00001eau	Download File View File

NONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 6. DESIGN OF A POTENT, INTRATRACHEALLY ACTIVE, PYRIDONE-BASED TRIFLUOROMETHYL KETONE

Ceccarelli, C.

(1995) J Med Chem 38: 212-215

Released	1995-02-07
Method	X-RAY DIFFRACTION 2 Å
Organisms	Sus scrofa
Macromolecule	PORCINE PANCREATIC ELASTASE (protein)
Unique Ligands	BDK, NA, SO4

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1ELA \| pdb_00001ela	Download File View File

Analogous inhibitors of elastase do not always bind analogously

Mattos, C., Rasmussen, B., Ding, X., Petsko, G.A., Ringe, D.

(1994) Nat Struct Biol 1: 55-58

Released	1994-04-30
Method	X-RAY DIFFRACTION 2 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	0Z1, ACY, CA, SO4

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1ELB \| pdb_00001elb	Download File View File

Analogous inhibitors of elastase do not always bind analogously

Mattos, C., Rasmussen, B., Ding, X., Petsko, G.A., Ringe, D.

(1994) Nat Struct Biol 1: 55-58

Released	1994-06-22
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	0Z4, CA, SO4

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1ELC \| pdb_00001elc	Download File View File

Analogous inhibitors of elastase do not always bind analogously

Mattos, C., Rasmussen, B., Ding, X., Petsko, G.A., Ringe, D.

(1994) Nat Struct Biol 1: 55-58

Released	1994-04-30
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	0Z3, CA

Explore in 3D

1ELD \| pdb_00001eld	Download File View File

Structural analysis of the active site of porcine pancreatic elastase based on the x-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors

Mattos, C., Petsko, G.A., Ringe, D.

(1995) Biochemistry 34: 3193-3203

Released	1995-02-14
Method	X-RAY DIFFRACTION 2 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	0Z0, ACY, CA

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1ELE \| pdb_00001ele	Download File View File

STRUCTURAL ANALYSIS OF THE ACTIVE SITE OF PORCINE PANCREATIC ELASTASE BASED ON THE X-RAY CRYSTAL STRUCTURES OF COMPLEXES WITH TRIFLUOROACETYL-DIPEPTIDE-ANILIDE INHIBITORS

Mattos, C., Petsko, G.A., Ringe, D.

(1995) Biochemistry 34: 3193-3203

Released	1995-02-14
Method	X-RAY DIFFRACTION 2 Å
Organisms	Sus scrofa
Macromolecule	ELASTASE (protein)
Unique Ligands	0QN, CA, SO4

Explore in 3D

1ELF \| pdb_00001elf	Download File View File

NATURE OF THE INACTIVATION OF ELASTASE BY N-PEPTIDYL-O-AROYL HYDROXYLAMINE AS A FUNCTION OF PH

Ding, X., Rasmussen, B., Demuth, H.-U., Ringe, D., Steinmetz, A.C.U.

(1995) Biochemistry 34: 7749-7756

Released	1995-07-10
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Sus scrofa
Macromolecule	PORCINE PANCREATIC ELASTASE (protein)
Unique Ligands	BAF, CA, SO4

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1ELG \| pdb_00001elg	Download File View File

NATURE OF THE INACTIVATION OF ELASTASE BY N-PEPTIDYL-O-AROYL HYDROXYLAMINE AS A FUNCTION OF PH

Ding, X., Rasmussen, B., Demuth, H.-U., Ringe, D., Steinmetz, A.C.U.

(1995) Biochemistry 34: 7749-7756

Released	1995-07-10
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Sus scrofa
Macromolecule	PORCINE PANCREATIC ELASTASE (protein)
Unique Ligands	BAA, CA

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1ELT \| pdb_00001elt	Download File View File

STRUCTURE OF NATIVE PANCREATIC ELASTASE FROM NORTH ATLANTIC SALMON AT 1.61 ANGSTROMS RESOLUTION

Berglund, G.I., Smalaas, A.O.

(1995) Acta Crystallogr D Biol Crystallogr 51: 925-937

Released	1996-01-01
Method	X-RAY DIFFRACTION 1.61 Å
Organisms	Salmo salar
Macromolecule	ELASTASE (protein)
Unique Ligands	CA

Explore in 3D

1ESA \| pdb_00001esa	Download File View File

DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE

Ding, X., Rasmussen, B., Petsko, G.A., Ringe, D.

(1994) Biochemistry 33: 9285-9293

Released	1994-04-30
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Sus scrofa
Macromolecule	PORCINE PANCREATIC ELASTASE (protein)
Unique Ligands	CA, SO4

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1ESB \| pdb_00001esb	Download File View File

DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE

Ding, X., Rasmussen, B., Petsko, G.A., Ringe, D.

(1994) Biochemistry 33: 9285-9293

Released	1994-04-30
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Sus scrofa
Macromolecule	PORCINE PANCREATIC ELASTASE (protein)
Unique Ligands	BBL, CA, SO4

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1EST \| pdb_00001est	Download File View File

THE ATOMIC STRUCTURE OF CRYSTALLINE PORCINE PANCREATIC ELASTASE AT 2.5 ANGSTROMS RESOLUTION. COMPARISONS WITH THE STRUCTURE OF ALPHA-CHYMOTRYPSIN

Sawyer, L., Shotton, D.M., Watson, H.C.

(1978) J Mol Biology 118: 137-208

Released	1976-05-27
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Sus scrofa
Macromolecule	PORCINE PANCREATIC ELASTASE (protein)
Unique Ligands	SO4, TSU

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1FLE \| pdb_00001fle	Download File View File

CRYSTAL STRUCTURE OF ELAFIN COMPLEXED WITH PORCINE PANCREATIC ELASTASE

Tsunemi, M., Matsuura, Y., Sakakibara, S., Katsube, Y.

(1996) Biochemistry 35: 11570-11576

Released	1997-01-11
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens Sus scrofa
Macromolecule	ELAFIN (protein) ELASTASE (protein)

1 to 25 of 128 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1B0E | pdb_00001b0e

1BMA | pdb_00001bma

1BTU | pdb_00001btu

1C1M | pdb_00001c1m

1E34 | pdb_00001e34

1E35 | pdb_00001e35

1E36 | pdb_00001e36

1E37 | pdb_00001e37

1E38 | pdb_00001e38

1EAI | pdb_00001eai

1EAS | pdb_00001eas

1EAT | pdb_00001eat

1EAU | pdb_00001eau

1ELA | pdb_00001ela

1ELB | pdb_00001elb

1ELC | pdb_00001elc

1ELD | pdb_00001eld

1ELE | pdb_00001ele

1ELF | pdb_00001elf

1ELG | pdb_00001elg

1ELT | pdb_00001elt

1ESA | pdb_00001esa

1ESB | pdb_00001esb

1EST | pdb_00001est

1FLE | pdb_00001fle