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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 3.5.4.4

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Search Summary

This query matches 70 Structures.

Refinements

Structure Determination Methodology

experimental (70)

Scientific Name of Source Organism

	Bos taurus (17)
	Mus musculus (12)
	Bacteroidales bacterium (8)
	Homo sapiens (6)
	Limisphaera ngatamarikiensis (4)
	Plasmodium vivax (4)
	Pseudomonas aeruginosa (4)
	Escherichia coli (3)
	Geobacillus stearothermophilus (3)
	Bacillus anthracis (1)

More...

Taxonomy

	Eukaryota (40)
	Bacteria (30)
	Riboviria (1)

Experimental Method

	X-RAY DIFFRACTION (61)
	ELECTRON MICROSCOPY (9)

Polymer Entity Type

	Protein (70)
	RNA (6)

Refinement Resolution (Å)

	1.0 - 1.5 (5)
	1.5 - 2.0 (11)
	2.0 - 2.5 (27)
	2.5 - 3.0 (16)
	3.0 - 3.5 (7)
	3.5 - 4.0 (4)

Release Date

	1990 - 1994 (1)
	1995 - 1999 (7)
	2000 - 2004 (14)
	2005 - 2009 (15)
	2010 - 2014 (13)
	2015 - 2019 (3)
	2020 - 2024 (17)

Enzyme Classification Name

	Hydrolases (70)
	Transferases (8)
	Oxidoreductases (3)

Symmetry Type

	Asymmetric (53)
	Cyclic (14)
	Dihedral (3)

SCOP Classification

	Alpha and beta proteins (a/b) (39)
	All beta proteins (2)
	Alpha and beta proteins (a+b) (6)
	Artifacts (3)

AllSelected

1 to 25 of 70 Structures

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1A4L \| pdb_00001a4l	Download File View File

ADA STRUCTURE COMPLEXED WITH DEOXYCOFORMYCIN AT PH 7.0

Wang, Z., Quiocho, F.A.

(1998) Biochemistry 37: 8314-8324

Released	1998-10-14
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Mus musculus
Macromolecule	ADENOSINE DEAMINASE (protein)
Unique Ligands	DCF, ZN

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1A4M \| pdb_00001a4m	Download File View File

ADA STRUCTURE COMPLEXED WITH PURINE RIBOSIDE AT PH 7.0

Wang, Z., Quiocho, F.A.

(1998) Biochemistry 37: 8314-8324

Released	1998-10-14
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Mus musculus
Macromolecule	ADENOSINE DEAMINASE (protein)
Unique Ligands	PRH, ZN

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1ADD \| pdb_00001add	Download File View File

A PRE-TRANSITION STATE MIMIC OF AN ENZYME: X-RAY STRUCTURE OF ADENOSINE DEAMINASE WITH BOUND 1-DEAZA-ADENOSINE AND ZINC-ACTIVATED WATER

Wilson, D.K., Quiocho, F.A.

(1993) Biochemistry 32: 1689-1694

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	ADENOSINE DEAMINASE (protein)
Unique Ligands	1DA, ZN

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1FKW \| pdb_00001fkw	Download File View File

MURINE ADENOSINE DEAMINASE (D295E)

Wilson, D.K., Quiocho, F.A.

(1996) Biochemistry 35: 7862-7872

Released	1996-08-01
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	ADENOSINE DEAMINASE (protein)
Unique Ligands	PUR, ZN

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1FKX \| pdb_00001fkx	Download File View File

MURINE ADENOSINE DEAMINASE (D296A)

Wilson, D.K., Quiocho, F.A.

(1996) Biochemistry 35: 7862-7872

Released	1996-08-01
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	ADENOSINE DEAMINASE (protein)
Unique Ligands	PRH, ZN

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1KRM \| pdb_00001krm	Download File View File

Crystal structure of bovine adenosine deaminase complexed with 6-hydroxyl-1,6-dihydropurine riboside

Kinoshita, T.

(2003) Acta Crystallogr D Biol Crystallogr 59: 299-303

Released	2003-01-14
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bos taurus
Macromolecule	adenosine deaminase (protein)
Unique Ligands	PRH, ZN

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1NDV \| pdb_00001ndv	Download File View File

Crystal Structure of Adenosine Deaminase complexed with FR117016

Kinoshita, T.

(2004) J Am Chem Soc 126: 34-35

Released	2003-12-09
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Bos taurus
Macromolecule	Adenosine deaminase (protein)
Unique Ligands	FR0, ZN

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1NDW \| pdb_00001ndw	Download File View File

Crystal Structure of Adenosine Deaminase Complexed with FR221647

Kinoshita, T.

(2004) J Am Chem Soc 126: 34-35

Released	2003-12-09
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	Adenosine Deaminase (protein)
Unique Ligands	FR2, ZN

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1NDY \| pdb_00001ndy	Download File View File

Crystal Structure of Adenosine Deaminase Complexed with FR230513

Kinoshita, T.

(2004) J Am Chem Soc 126: 34-35

Released	2003-12-09
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	Adenosine Deaminase (protein)
Unique Ligands	FR3, ZN

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1NDZ \| pdb_00001ndz	Download File View File

Crystal Structure of Adenosine Deaminase Complexed with FR235999

Kinoshita, T.

(2004) J Am Chem Soc 126: 34-35

Released	2003-12-09
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	Adenosine Deaminase (protein)
Unique Ligands	FR5, ZN

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1O5R \| pdb_00001o5r	Download File View File

Crystal structure of adenosine deaminase complexed with a potent inhibitor

Kinoshita, T.

(2004) J Med Chem 47: 3730-3743

Released	2004-09-21
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Bos taurus
Macromolecule	Adenosine deaminase (protein)
Unique Ligands	FR9, ZN

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1QXL \| pdb_00001qxl	Download File View File

Crystal structure of Adenosine deaminase complexed with FR235380

Kinoshita, T.

(2004) J Med Chem 47: 3730-3743

Released	2004-09-21
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Bos taurus
Macromolecule	Adenosine deaminase (protein)
Unique Ligands	FR8, ZN

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1T8H \| pdb_00001t8h	Download File View File

1.8 A CRYSTAL STRUCTURE OF AN UNCHARACTERIZED B. STEAROTHERMOPHILUS PROTEIN

Minasov, G., Shuvalova, L., Mondragon, A., Taneja, B., Moy, S.F., Collart, F.R., Anderson, W.F., Midwest Center for Structural Genomics (MCSG)

To be published

Released	2004-05-18
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Geobacillus stearothermophilus
Macromolecule	YlmD protein sequence homologue (protein)
Unique Ligands	BME, ZN

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1U05 \| pdb_00001u05	Download File View File

Crystal structure of protein yfiH from Shigella flexneri, Pfam DUF152

Seetharaman, J., Swaminathan, S., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

To be published

Released	2004-08-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Shigella flexneri
Macromolecule	orf, conserved hypothetical protein (protein)
Unique Ligands	ZN

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1UIO \| pdb_00001uio	Download File View File

ADENOSINE DEAMINASE (HIS 238 ALA MUTANT)

Wilson, D.K., Quiocho, F.A.

(1996) Biochemistry 35: 15019-15028

Released	1997-06-24
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	ADENOSINE DEAMINASE (protein)
Unique Ligands	HPR, ZN

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1UIP \| pdb_00001uip	Download File View File

ADENOSINE DEAMINASE (HIS 238 GLU MUTANT)

Wilson, D.K., Quiocho, F.A.

(1996) Biochemistry 35: 15019-15028

Released	1997-06-24
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	ADENOSINE DEAMINASE (protein)
Unique Ligands	PUR, ZN

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1UML \| pdb_00001uml	Download File View File

Crystal structure of adenosine deaminase complexed with a potent inhibitor FR233624

Kinoshita, T.

(2004) J Med Chem 47: 3730-3743

Released	2004-09-21
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bos taurus
Macromolecule	Adenosine deaminase (protein)
Unique Ligands	FR4, ZN

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1V79 \| pdb_00001v79	Download File View File

Crystal structures of adenosine deaminase complexed with potent inhibitors

Kinoshita, T.

(2004) J Med Chem 47: 2728-2731

Released	2004-12-21
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bos taurus
Macromolecule	Adenosine deaminase (protein)
Unique Ligands	FR7, ZN

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1V7A \| pdb_00001v7a	Download File View File

Crystal structures of adenosine deaminase complexed with potent inhibitors

Kinoshita, T.

(2004) J Med Chem 47: 2728-2731

Released	2004-12-21
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bos taurus
Macromolecule	adenosine deaminase (protein)
Unique Ligands	FRC, ZN

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1VFL \| pdb_00001vfl	Download File View File

Adenosine deaminase

Kinoshita, T.

(2005) Biochemistry 44: 10562-10569

Released	2005-08-16
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Bos taurus
Macromolecule	Adenosine deaminase (protein)
Unique Ligands	ZN

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1W1I \| pdb_00001w1i	Download File View File

Crystal structure of dipeptidyl peptidase IV (DPPIV or CD26) in complex with adenosine deaminase

Weihofen, W.A., Liu, J., Reutter, W., Saenger, W., Fan, H.

(2004) J Biological Chem 279: 43330-43335

Released	2004-09-02
Method	X-RAY DIFFRACTION 3.03 Å
Organisms	Bos taurus Homo sapiens
Macromolecule	ADENOSINE DEAMINASE (protein) DIPEPTIDYL PEPTIDASE IV (protein)
Unique Ligands	NAG, ZN
Unique branched monosaccharides	BMA, FUC, MAN, NAG

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1WXY \| pdb_00001wxy	Download File View File

Crystal structure of adenosine deaminase ligated with a potent inhibitor

Kinoshita, T.

(2005) Biochemistry 44: 10562-10569

Released	2005-08-16
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bos taurus
Macromolecule	Adenosine deaminase (protein)
Unique Ligands	FRK, ZN

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1WXZ \| pdb_00001wxz	Download File View File

Crystal structure of adenosine deaminase ligated with a potent inhibitor

Kinoshita, T.

(2005) J Med Chem 48: 4750-4753

Released	2005-08-16
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Bos taurus
Macromolecule	Adenosine deaminase (protein)
Unique Ligands	FRL, ZN

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1XAF \| pdb_00001xaf	Download File View File

Crystal Structure of Protein of Unknown Function YfiH from Shigella flexneri 2a str. 2457T

Kim, Y., Maltseva, N., Dementieva, I., Collart, F., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)

(2006) Proteins 63: 1097-1101

Released	2004-08-31
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Shigella flexneri 2a str. 2457T
Macromolecule	orf, conserved hypothetical protein (protein)
Unique Ligands	ACT, GOL, ZN

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1Z9T \| pdb_00001z9t	Download File View File

CRYSTAL STRUCTURE OF A PUTATIVE LACCASE (YFIH) FROM ESCHERICHIA COLI AT 1.54 A RESOLUTION

Joint Center for Structural Genomics (JCSG)

To be published

Released	2005-04-12
Method	X-RAY DIFFRACTION 1.54 Å
Organisms	Escherichia coli
Macromolecule	Hypothetical UPF0124 protein yfiH (protein)
Unique Ligands	CIT, EDO

1 to 25 of 70 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1A4L | pdb_00001a4l

1A4M | pdb_00001a4m

1ADD | pdb_00001add

1FKW | pdb_00001fkw

1FKX | pdb_00001fkx

1KRM | pdb_00001krm

1NDV | pdb_00001ndv

1NDW | pdb_00001ndw

1NDY | pdb_00001ndy

1NDZ | pdb_00001ndz

1O5R | pdb_00001o5r

1QXL | pdb_00001qxl

1T8H | pdb_00001t8h

1U05 | pdb_00001u05

1UIO | pdb_00001uio

1UIP | pdb_00001uip

1UML | pdb_00001uml

1V79 | pdb_00001v79

1V7A | pdb_00001v7a

1VFL | pdb_00001vfl

1W1I | pdb_00001w1i

1WXY | pdb_00001wxy

1WXZ | pdb_00001wxz

1XAF | pdb_00001xaf

1Z9T | pdb_00001z9t