2KUZ | pdb_00002kuz

2-Aminopurine incorporation perturbs the dynamics and structure of DNA

PDB DOI: https://doi.org/10.2210/pdb2KUZ/pdb
NAKB: 2KUZ

Classification: DNA
Mutation(s): No

Deposited: 2010-03-03 Released: 2010-07-28
Deposition Author(s): Dallmann, A., Dehmel, L., Peters, T., Muegge, C., Griesinger, C.P., Tuma, J., Ernsting, N.P.

Experimental Data Snapshot

Method: SOLUTION NMR
Conformers Calculated: 100
Conformers Submitted: 11
Selection Criteria: structures with the lowest energy

wwPDB Validation 3D Report Full Report

This is version 1.2 of the entry. See complete history.

Literature

2-aminopurine incorporation perturbs the dynamics and structure of DNA.

Dallmann, A., Dehmel, L., Peters, T., Mugge, C., Griesinger, C., Tuma, J., Ernsting, N.P.

(2010) Angew Chem Int Ed Engl 49: 5989-5992

PubMed: 20632340 Search on PubMed
DOI: https://doi.org/10.1002/anie.201001312
Primary Citation of Related Structures:
2KUZ, 2KV0

Organizational Affiliation

Humboldt Universität zu Berlin, Institut für Chemie, 12489 Berlin, Germany.

Macromolecule Content

Total Structure Weight: 7.94 kDa
Atom Count: 527
Modelled Residue Count: 26
Deposited Residue Count: 26
Unique nucleic acid chains: 2

Macromolecules

Find similar nucleic acids by: Sequence | 3D Structure

Entity ID: 1
Molecule	Chains	Length	Organism	Image
DNA (5'-D(GPCPTPGPCPAPAPAPCPGPTPCP*G)-3')	A	13	N/A
Sequence Annotations Expand
Reference Sequence LOADING

Find similar nucleic acids by: Sequence | 3D Structure

Entity ID: 2
Molecule	Chains	Length	Organism	Image
DNA (5'-D(CPGPAPCPGPTPTPTPGPCPAPGP*C)-3')	B	13	N/A
Sequence Annotations Expand
Reference Sequence LOADING

Experimental Data & Validation

Experimental Data

Method: SOLUTION NMR
Conformers Calculated: 100
Conformers Submitted: 11
Selection Criteria: structures with the lowest energy

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2010-07-28

Deposition Author(s):

Griesinger, C.P.

Revision History (Full details and data files)

Version 1.0: 2010-07-28
Type: Initial release
Version 1.1: 2011-07-13
Changes: Version format compliance
Version 1.2: 2024-05-01
Changes: Data collection, Database references

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.