2VXP | pdb_00002vxp

The fourth FAS1 domain structure of human Bigh3

PDB DOI: https://doi.org/10.2210/pdb2VXP/pdb

Classification: CELL ADHESION
Organism(s): Homo sapiens
Expression System: Escherichia coli BL21(DE3)
Mutation(s): No

Deposited: 2008-07-08 Released: 2009-07-21
Deposition Author(s): Yoo, J.-H., Cho, H.-S.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.50 Å
R-Value Free:
0.285 (Depositor), 0.290 (DCC)
R-Value Work:
0.270 (Depositor), 0.270 (DCC)
R-Value Observed:
0.270 (Depositor)

wwPDB Validation 3D Report Full Report

This is version 1.3 of the entry. See complete history.

Literature

The Structural Analysis of the Fas1 Domain 4 of Big-H3 for Relationship with Corneal Dystrophy

Yoo, J.-H., Kim, E., Kim, J., Cho, H.-S.

To be published.

Macromolecule Content

Total Structure Weight: 28.51 kDa
Atom Count: 2,010
Modelled Residue Count: 262
Deposited Residue Count: 264
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3	A, B	132	Homo sapiens	Mutation(s): 0
UniProt & NIH Common Fund Data Resources
Find proteins for Q15582 (Homo sapiens) Explore Q15582 Go to UniProtKB: Q15582
PHAROS: Q15582 GTEx: ENSG00000120708
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q15582
Sequence Annotations Expand
Reference Sequence LOADING

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 2.50 Å
R-Value Free: 0.285 (Depositor), 0.290 (DCC)
R-Value Work: 0.270 (Depositor), 0.270 (DCC)
R-Value Observed: 0.270 (Depositor)

Space Group: P 6₅

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 62.934	α = 90
b = 62.934	β = 90
c = 143.29	γ = 120

Software Package:

Software Name	Purpose
CNS	refinement
DENZO	data reduction
SCALEPACK	data scaling
MOLREP	phasing

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2009-07-21

Deposition Author(s):

Revision History (Full details and data files)

Version 1.0: 2009-07-21
Type: Initial release
Version 1.1: 2011-05-07
Changes: Version format compliance
Version 1.2: 2011-07-13
Changes: Version format compliance
Version 1.3: 2024-05-08
Changes: Data collection, Database references, Other

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.