Download MendeleyGlutamate gating of AMPA-subtype iGluRs at physiological temperatures
Kumar Mondal, A., Carrillo, E., Jayarman, V., Twomey, E.C.(2025) Nature
9DHP | pdb_00009dhp
Resting state 1 of the GluA2-gamma2 complex
- PDB DOI: https://doi.org/10.2210/pdb9DHP/pdb
- EM Map EMD-46872: EMDB EMDataResource
- Classification: TRANSPORT PROTEIN
- Organism(s): Rattus norvegicus, Mus musculus
- Expression System: Homo sapiens
- Mutation(s): No
- Membrane Protein: Yes PDBTM
- Deposited: 2024-09-04 Released: 2025-03-26
- Funding Organization(s): National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS), Other private
Experimental Data Snapshot
- Method: ELECTRON MICROSCOPY
- Resolution: 4.18 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Isoform Flip of Glutamate receptor 2 | 430 | Rattus norvegicus | Mutation(s): 0 Gene Names: Gria2, GluA2, Glur2 Membrane Entity: Yes |  | |
UniProt | |||||
Find proteins for P19491 (Rattus norvegicus) Explore P19491 Go to UniProtKB: P19491 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P19491 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Voltage-dependent calcium channel gamma-2 subunit | 205 | Mus musculus | Mutation(s): 0 Gene Names: Cacng2, Stg Membrane Entity: Yes |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O88602 (Mus musculus) Explore O88602 Go to UniProtKB: O88602 | |||||
IMPC: MGI:1316660 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O88602 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: ELECTRON MICROSCOPY
- Resolution: 4.18 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
Entry History & Funding Information
Deposition Data
- Released Date: 2025-03-26 Deposition Author(s): Kumar Mondal, A., Carrillo, E., Jayaraman, V., Twomey, E.C.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | R35GM154904 |
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | R35GM122528 |
| Other private | Kinship Foundation 22098168 | |
| Other private | Diana Helis Henry Medical Research Foundation 142548 |
Revision History (Full details and data files)
- Version 1.0: 2025-03-26
Type: Initial release
