3J2M | pdb_00003j2m

The X-ray structure of the gp15 hexamer and the model of the gp18 protein fitted into the cryo-EM reconstruction of the extended T4 tail

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Phage tail protein-like	8092774	3001913	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Phage tail protein-like	8092774	3001913	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Phage tail protein-like	8092774	3001913	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Phage tail protein-like	8092774	3001913	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Phage tail protein-like	8092774	3001913	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Phage tail protein-like	8092774	3001913	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	T4-gp15_tss	e3j2mA1	A: a+b two layers	X: Alpha-beta plaits	H: Phage tail protein-like (From Topology)	T: Phage tail protein-like	F: T4-gp15_tss	ECOD (1.6)
B	T4-gp15_tss	e3j2mB1	A: a+b two layers	X: Alpha-beta plaits	H: Phage tail protein-like (From Topology)	T: Phage tail protein-like	F: T4-gp15_tss	ECOD (1.6)
C	T4-gp15_tss	e3j2mC1	A: a+b two layers	X: Alpha-beta plaits	H: Phage tail protein-like (From Topology)	T: Phage tail protein-like	F: T4-gp15_tss	ECOD (1.6)
D	T4-gp15_tss	e3j2mD1	A: a+b two layers	X: Alpha-beta plaits	H: Phage tail protein-like (From Topology)	T: Phage tail protein-like	F: T4-gp15_tss	ECOD (1.6)
E	T4-gp15_tss	e3j2mE1	A: a+b two layers	X: Alpha-beta plaits	H: Phage tail protein-like (From Topology)	T: Phage tail protein-like	F: T4-gp15_tss	ECOD (1.6)
F	T4-gp15_tss	e3j2mF1	A: a+b two layers	X: Alpha-beta plaits	H: Phage tail protein-like (From Topology)	T: Phage tail protein-like	F: T4-gp15_tss	ECOD (1.6)
G [auth U]	18	e3j2mU3	A: beta sandwiches	X: jelly-roll	H: Domain I of tail sheath protein Gp18 (From Topology)	T: Domain I of tail sheath protein Gp18	F: 18	ECOD (1.6)
G [auth U]	Phage_sheath_1N_1	e3j2mU2	A: a+b complex topology	X: Domain II in tail sheath protein Gp18 (From Topology)	H: Domain II in tail sheath protein Gp18 (From Topology)	T: Domain II in tail sheath protein Gp18	F: Phage_sheath_1N_1	ECOD (1.6)
G [auth U]	Phage_sheath_1C	e3j2mU4	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: Phage_sheath_1C	ECOD (1.6)
G [auth U]	Phage_sheath_1	e3j2mU1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: Phage_sheath_1	ECOD (1.6)
H [auth V]	18	e3j2mV7	A: beta sandwiches	X: jelly-roll	H: Domain I of tail sheath protein Gp18 (From Topology)	T: Domain I of tail sheath protein Gp18	F: 18	ECOD (1.6)
H [auth V]	Phage_sheath_1N_1	e3j2mV5	A: a+b complex topology	X: Domain II in tail sheath protein Gp18 (From Topology)	H: Domain II in tail sheath protein Gp18 (From Topology)	T: Domain II in tail sheath protein Gp18	F: Phage_sheath_1N_1	ECOD (1.6)
H [auth V]	Phage_sheath_1C	e3j2mV8	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: Phage_sheath_1C	ECOD (1.6)
H [auth V]	Phage_sheath_1	e3j2mV6	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: Phage_sheath_1	ECOD (1.6)
I [auth W]	18	e3j2mW7	A: beta sandwiches	X: jelly-roll	H: Domain I of tail sheath protein Gp18 (From Topology)	T: Domain I of tail sheath protein Gp18	F: 18	ECOD (1.6)
I [auth W]	Phage_sheath_1N_1	e3j2mW5	A: a+b complex topology	X: Domain II in tail sheath protein Gp18 (From Topology)	H: Domain II in tail sheath protein Gp18 (From Topology)	T: Domain II in tail sheath protein Gp18	F: Phage_sheath_1N_1	ECOD (1.6)
I [auth W]	Phage_sheath_1C	e3j2mW8	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: Phage_sheath_1C	ECOD (1.6)
I [auth W]	Phage_sheath_1	e3j2mW6	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: Phage_sheath_1	ECOD (1.6)
J [auth X]	18	e3j2mX7	A: beta sandwiches	X: jelly-roll	H: Domain I of tail sheath protein Gp18 (From Topology)	T: Domain I of tail sheath protein Gp18	F: 18	ECOD (1.6)
J [auth X]	Phage_sheath_1N_1	e3j2mX5	A: a+b complex topology	X: Domain II in tail sheath protein Gp18 (From Topology)	H: Domain II in tail sheath protein Gp18 (From Topology)	T: Domain II in tail sheath protein Gp18	F: Phage_sheath_1N_1	ECOD (1.6)
J [auth X]	Phage_sheath_1C	e3j2mX8	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: Phage_sheath_1C	ECOD (1.6)
J [auth X]	Phage_sheath_1	e3j2mX6	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: Phage_sheath_1	ECOD (1.6)
K [auth Y]	18	e3j2mY7	A: beta sandwiches	X: jelly-roll	H: Domain I of tail sheath protein Gp18 (From Topology)	T: Domain I of tail sheath protein Gp18	F: 18	ECOD (1.6)
K [auth Y]	Phage_sheath_1N_1	e3j2mY5	A: a+b complex topology	X: Domain II in tail sheath protein Gp18 (From Topology)	H: Domain II in tail sheath protein Gp18 (From Topology)	T: Domain II in tail sheath protein Gp18	F: Phage_sheath_1N_1	ECOD (1.6)
K [auth Y]	Phage_sheath_1C	e3j2mY8	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: Phage_sheath_1C	ECOD (1.6)
K [auth Y]	Phage_sheath_1	e3j2mY6	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: Phage_sheath_1	ECOD (1.6)
L [auth Z]	18	e3j2mZ7	A: beta sandwiches	X: jelly-roll	H: Domain I of tail sheath protein Gp18 (From Topology)	T: Domain I of tail sheath protein Gp18	F: 18	ECOD (1.6)
L [auth Z]	Phage_sheath_1N_1	e3j2mZ5	A: a+b complex topology	X: Domain II in tail sheath protein Gp18 (From Topology)	H: Domain II in tail sheath protein Gp18 (From Topology)	T: Domain II in tail sheath protein Gp18	F: Phage_sheath_1N_1	ECOD (1.6)
L [auth Z]	Phage_sheath_1C	e3j2mZ8	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: Phage_sheath_1C	ECOD (1.6)
L [auth Z]	Phage_sheath_1	e3j2mZ6	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: Phage_sheath_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	PF17482	Phage tail sheath C-terminal domain (Phage_sheath_1C)	Phage tail sheath C-terminal domain	This entry represents the C-terminal domain in a variety of phage tail sheath proteins [4].	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	PF17481	Phage tail sheath protein beta-sandwich domain (Phage_sheath_domII)	Phage tail sheath protein beta-sandwich domain	This entry represents a two-layer beta sandwich domain found in a variety of phage tail sheath proteins, referred to as domain II in [4,5]. Domain I and II form the protease-resistant fragment [5].	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	PF22671	Tail sheath protein Gp18 domain III N-terminal region (Gp18_domIII_N)	Tail sheath protein Gp18 domain III N-terminal region	This entry represents the N-terminal segment of domain III from the phage tail sheath protein Gp18 y similar sequences [1-5]. Domain III is completed by Pfam:PF04984 with an overall structure consisting of a beta-sheet with five parallel and one anti ...	This entry represents the N-terminal segment of domain III from the phage tail sheath protein Gp18 y similar sequences [1-5]. Domain III is completed by Pfam:PF04984 with an overall structure consisting of a beta-sheet with five parallel and one anti-parallel beta-strands plus six alpha-helices, which surround the beta-sheet.	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	PF04984	Phage tail sheath protein subtilisin-like domain (Phage_sheath_1)	Phage tail sheath protein subtilisin-like domain	This entry represents the second domain in a variety of phage tail sheath proteins. According to ECOD this domain has a subtilisin-like structure.	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	PF22639	Tail sheath protein Gp18-like domain I (Gp18_dom_I)	Tail sheath protein Gp18-like domain I	This entry represents domain I from bacteriophage tail sheath proteins such as Gp18, a protein that surrounds the central non-contractile tail tube of the tail sheath from bacteriophages, which contracts during infection [1,2]. These proteins consist ...	This entry represents domain I from bacteriophage tail sheath proteins such as Gp18, a protein that surrounds the central non-contractile tail tube of the tail sheath from bacteriophages, which contracts during infection [1,2]. These proteins consist of three domains, domains I, II (Pfam:PF17481) and III (Pfam:PF17482). Domains I and II form the protease-resistant fragment [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Tail connector protein Gp15	-	-	virion component
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	Tail sheath protein Gp18	-	symbiont genome ejection through host cell envelope biological process involved in interspecies interaction between organisms symbiont entry into host cell viral process symbiont entry into host viral life cycle symbiont genome ejection through host cell envelope, contractile tail mechanism biological process involved in interaction with host biological process involved in symbiotic interaction	virus tail virion component virus tail, sheath

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR031997	Myoviridae tail sheath stabiliser	Family
A, B, C, D, E A, B, C, D, E, F	IPR038553	Myoviridae tail sheath stabiliser superfamily	Homologous Superfamily
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	IPR054565	Tail sheath protein Gp18-like, domain I	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	IPR020287	Tail sheath protein, C-terminal domain	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	IPR054564	Tail sheath protein Gp18-like, domain III N-terminal region	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	IPR035089	Tail sheath protein, subtilisin-like domain	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	IPR035326	Phage tail sheath protein-like, beta-sandwich domain	Domain
G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], G [auth U], H [auth V], I [auth W], J [auth X], K [auth Y], L [auth Z]	IPR052042	Bacteriophage Tail Sheath Structural Protein	Family