5NWK

14-3-3c in complex with CPP and fusicoccin

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C [auth B]	SCOP2B Superfamily	14-3-3 protein	8033898	3001329	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	14-3-3 protein	8033898	3001329	SCOP2B (2022-06-29)
E [auth C]	SCOP2B Superfamily	14-3-3 protein	8033898	3001329	SCOP2B (2022-06-29)
G [auth D]	SCOP2B Superfamily	14-3-3 protein	8033898	3001329	SCOP2B (2022-06-29)
I [auth E]	SCOP2B Superfamily	14-3-3 protein	8033898	3001329	SCOP2B (2022-06-29)
K [auth F]	SCOP2B Superfamily	14-3-3 protein	8033898	3001329	SCOP2B (2022-06-29)
M [auth G]	SCOP2B Superfamily	14-3-3 protein	8033898	3001329	SCOP2B (2022-06-29)
O [auth H]	SCOP2B Superfamily	14-3-3 protein	8033898	3001329	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C [auth B]	14-3-3	e5nwkB1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: 14-3-3	ECOD (1.6)
A	14-3-3	e5nwkA1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: 14-3-3	ECOD (1.6)
E [auth C]	14-3-3	e5nwkC1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: 14-3-3	ECOD (1.6)
G [auth D]	14-3-3	e5nwkD1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: 14-3-3	ECOD (1.6)
I [auth E]	14-3-3	e5nwkE1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: 14-3-3	ECOD (1.6)
K [auth F]	14-3-3	e5nwkF1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: 14-3-3	ECOD (1.6)
M [auth G]	14-3-3	e5nwkG1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: 14-3-3	ECOD (1.6)
O [auth H]	14-3-3	e5nwkH1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: 14-3-3	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C [auth B]	1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin	domain 1	CATH (4.3.0)
A	1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin	domain 1	CATH (4.3.0)
E [auth C]	1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin	domain 1	CATH (4.3.0)
G [auth D]	1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin	domain 1	CATH (4.3.0)
I [auth E]	1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin	domain 1	CATH (4.3.0)
K [auth F]	1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin	domain 1	CATH (4.3.0)
M [auth G]	1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin	domain 1	CATH (4.3.0)
O [auth H]	1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C [auth B], E [auth C], G [auth D], I [auth E], A, C [auth B], E [auth C], G [auth D], I [auth E], K [auth F], M [auth G], O [auth H]	PF00244	14-3-3 protein (14-3-3)	14-3-3 protein	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C [auth B], E [auth C], G [auth D], I [auth E], A, C [auth B], E [auth C], G [auth D], I [auth E], K [auth F], M [auth G], O [auth H]	14-3-3 c-1 protein	-	protein localization localization cellular localization cellular macromolecule localization macromolecule localization cellular process cellular response to stimulus regulation of biological process regulation of cellular process response to stimulus signaling biological regulation signal transduction cell communication	cellular anatomical structure intracellular anatomical structure cytoplasm
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	Potassium channel KAT1	inward rectifier potassium channel activity monoatomic cation transmembrane transporter activity gated channel activity monoatomic ion channel activity potassium ion transmembrane transporter activity voltage-gated channel activity voltage-gated monoatomic ion channel activity potassium channel activity voltage-gated monoatomic cation channel activity ligand-gated channel activity ligand-gated monoatomic ion channel activity monoatomic cation channel activity passive transmembrane transporter activity voltage-gated potassium channel activity inorganic molecular entity transmembrane transporter activity inward rectifier potassium channel activity monoatomic cation transmembrane transporter activity gated channel activity monoatomic ion channel activity potassium ion transmembrane transporter activity voltage-gated channel activity voltage-gated monoatomic ion channel activity potassium channel activity voltage-gated monoatomic cation channel activity ligand-gated channel activity ligand-gated monoatomic ion channel activity monoatomic cation channel activity passive transmembrane transporter activity voltage-gated potassium channel activity inorganic molecular entity transmembrane transporter activity channel activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity metal ion transmembrane transporter activity ligand-gated monoatomic cation channel activity transmembrane transporter activity identical protein binding protein binding binding	-	cell periphery cellular anatomical structure plasma membrane membrane protein-containing complex transmembrane transporter complex membrane protein complex transporter complex monoatomic ion channel complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C [auth B], E [auth C], G [auth D], I [auth E], A, C [auth B], E [auth C], G [auth D], I [auth E], K [auth F], M [auth G], O [auth H]	IPR036815	14-3-3 domain superfamily	Homologous Superfamily
A, C [auth B], E [auth C], G [auth D], I [auth E], A, C [auth B], E [auth C], G [auth D], I [auth E], K [auth F], M [auth G], O [auth H]	IPR000308	14-3-3 protein	Family
A, C [auth B], E [auth C], G [auth D], I [auth E], A, C [auth B], E [auth C], G [auth D], I [auth E], K [auth F], M [auth G], O [auth H]	IPR023409	14-3-3 protein, conserved site	Conserved Site
A, C [auth B], E [auth C], G [auth D], I [auth E], A, C [auth B], E [auth C], G [auth D], I [auth E], K [auth F], M [auth G], O [auth H]	IPR023410	14-3-3 domain	Domain
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	IPR005821	Ion transport domain	Domain
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	IPR003938	Potassium channel, voltage-dependent, EAG/ELK/ERG-like	Family
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	IPR021789	KHA domain	Domain
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	IPR045319	Potassium channel KAT/AKT	Family
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	IPR000595	Cyclic nucleotide-binding domain	Domain
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	IPR018490	Cyclic nucleotide-binding domain superfamily	Homologous Superfamily
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	IPR014710	RmlC-like jelly roll fold	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], B [auth P], D [auth Q], F [auth R], H [auth S], J [auth T], L [auth U], N [auth V], P [auth W]	SEP	Parent Component: SER RESID: AA0037 PSI-MOD : O-phospho-L-serine MOD:00046

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.