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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Josephs, M.B."

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Search Summary

This query matches 8 Structures.

Refinements

Structure Determination Methodology

experimental (8)

Scientific Name of Source Organism

Homo sapiens (8)

Taxonomy

Eukaryota (8)

Experimental Method

	X-RAY DIFFRACTION (5)
	SOLUTION NMR (3)

Polymer Entity Type

Protein (8)

Refinement Resolution (Å)

	1.5 - 2.0 (2)
	2.0 - 2.5 (2)
	2.5 - 3.0 (1)

Release Date

2005 - 2009 (8)

Enzyme Classification Name

Hydrolases (8)

Symmetry Type

Asymmetric (8)

SCOP Classification

	Alpha and beta proteins (a/b) (4)
	Alpha and beta proteins (a+b) (3)

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1 to 8 of 8 Structures

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2BYE \| pdb_00002bye	Download File View File

NMR solution structure of phospholipase c epsilon RA 1 domain

Bunney, T.D., Harris, R., Gandarillas, N.L., Josephs, M.B., Roe, S.M., Paterson, H.F., Rodrigues-Lima, F., Esposito, D., Gieschik, P., Pearl, L.H., Driscoll, P.C., Katan, M.

(2006) Mol Cell 21: 495

Released	2006-02-22
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	PHOSPHOLIPASE C, EPSILON 1 (protein)

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2BYF \| pdb_00002byf	Download File View File

NMR solution structure of phospholipase c epsilon RA 2 domain

Bunney, T.D., Harris, R., Gandarillas, N.L., Josephs, M.B., Roe, S.M., Paterson, H.F., Rodrigues-Lima, F., Esposito, D., Gieschik, P., Pearl, L.H., Driscoll, P.C., Katan, M.

(2006) Mol Cell 21: 495

Released	2006-02-22
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	PHOSPHOLIPASE C, EPSILON 1 (protein)

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2C5L \| pdb_00002c5l	Download File View File

Structure of PLC epsilon Ras association domain with hRas

Roe, S.M., Bunney, T.D., Katan, M., Pearl, L.H.

(2006) Mol Cell 21: 495

Released	2006-02-20
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	GTPASE HRAS (protein) PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C PLC-EPSILON (protein)
Unique Ligands	GOL, GTP, MG

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2K2J \| pdb_00002k2j	Download File View File

NMR solution structure of the split PH domain from Phospholipase C gamma 2

Harris, R., Bunney, T.D., Katan, M., Driscoll, P.C.

(2008) J Biological Chem 283: 30351-30362

Released	2008-09-09
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 (protein)

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2W2T \| pdb_00002w2t	Download File View File

Rac2 (G12V) in complex with GDP

Opaleye, O., Bunney, T.D., Roe, S.M., Pearl, L.H.

(2009) Mol Cell 34: 223

Released	2009-05-05
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 (protein)
Unique Ligands	GDP, MG

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2W2V \| pdb_00002w2v	Download File View File

Rac2 (G12V) in complex with GTPgS

Opaleye, O., Bunney, T.D., Roe, S.M., Pearl, L.H.

(2009) Mol Cell 34: 223

Released	2009-05-05
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 (protein)
Unique Ligands	GTP

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2W2W \| pdb_00002w2w	Download File View File

PLCg2 Split Pleckstrin Homology (PH) Domain

Opaleye, O., Bunney, T.D., Roe, S.M., Pearl, L.H.

(2009) Mol Cell 34: 223

Released	2009-05-05
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 (protein)

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2W2X \| pdb_00002w2x	Download File View File

Complex of Rac2 and PLCg2 spPH Domain

Opaleye, O., Bunney, T.D., Roe, S.M., Pearl, L.H.

(2009) Mol Cell 34: 223

Released	2009-05-05
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 (protein) RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 (protein)
Unique Ligands	GSP, MG

1 to 8 of 8 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

2BYE | pdb_00002bye

NMR solution structure of phospholipase c epsilon RA 1 domain

2BYF | pdb_00002byf

NMR solution structure of phospholipase c epsilon RA 2 domain

2C5L | pdb_00002c5l

Structure of PLC epsilon Ras association domain with hRas

2K2J | pdb_00002k2j

NMR solution structure of the split PH domain from Phospholipase C gamma 2

2W2T | pdb_00002w2t

Rac2 (G12V) in complex with GDP

2W2V | pdb_00002w2v

Rac2 (G12V) in complex with GTPgS

2W2W | pdb_00002w2w

PLCg2 Split Pleckstrin Homology (PH) Domain

2W2X | pdb_00002w2x

Complex of Rac2 and PLCg2 spPH Domain

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

2BYE | pdb_00002bye

2BYF | pdb_00002byf

2C5L | pdb_00002c5l

2K2J | pdb_00002k2j

2W2T | pdb_00002w2t

2W2V | pdb_00002w2v

2W2W | pdb_00002w2w

2W2X | pdb_00002w2x