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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 6.3.4.4

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Search Summary

This query matches 53 Structures.

Refinements

Structure Determination Methodology

experimental (53)

Scientific Name of Source Organism

	Escherichia coli (15)
	Escherichia coli K-12 (9)
	Mus musculus (9)
	Helicobacter pylori 26695 (4)
	Bacillus anthracis str. 'Ames Ancestor (2)
	Cryptococcus neoformans var. grubii H99 (2)
	Legionella pneumophila (2)
	Pyrococcus horikoshii OT3 (2)
	Arabidopsis thaliana (1)
	Burkholderia thailandensis E264 (1)

More...

Taxonomy

	Bacteria (36)
	Eukaryota (15)
	Archaea (2)

Experimental Method

X-RAY DIFFRACTION (53)

Polymer Entity Type

Protein (53)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (9)
	2.0 - 2.5 (20)
	2.5 - 3.0 (22)
	3.0 - 3.5 (1)

Release Date

	1995 - 1999 (19)
	2000 - 2004 (15)
	2005 - 2009 (5)
	2010 - 2014 (4)
	2015 - 2019 (5)
	2020 - 2024 (5)

Enzyme Classification Name

Ligases (53)

Symmetry Type

	Cyclic (52)
	Asymmetric (3)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a/b) (47)
	Artifacts (2)

AllSelected

1 to 25 of 53 Structures

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1ADE \| pdb_00001ade	Download File View File

STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE PH 7 AT 25 DEGREES CELSIUS

Silva, M.M., Poland, B.W., Hoffman, C.M., Fromm, H.J., Honzatko, R.B.

(1995) J Mol Biology 254: 431-446

Released	1996-01-29
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)

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1ADI \| pdb_00001adi	Download File View File

STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE AT PH 6.5 AND 25 DEGREES CELSIUS

Silva, M.M., Poland, B.W., Hoffman, C.M., Fromm, H.J., Honzatko, R.B.

(1995) J Mol Biology 254: 431-446

Released	1996-06-10
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)

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1CG0 \| pdb_00001cg0	Download File View File

STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH HADACIDIN, GDP, 6-PHOSPHORYL-IMP, AND MG2+

Choe, J.Y., Poland, B.W., Fromm, H., Honzatko, R.

(1999) Biochemistry 38: 6953-6961

Released	1999-06-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli K-12
Macromolecule	PROTEIN (ADENYLOSUCCINATE SYNTHETASE) (protein)
Unique Ligands	GDP, HDA, IMO, MG

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1CG1 \| pdb_00001cg1	Download File View File

STRUCTURE OF THE MUTANT (K16Q) OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH HADACIDIN, GDP, 6-PHOSPHORYL-IMP, AND MG2+

Choe, J.Y., Poland, B.W., Fromm, H., Honzatko, R.

(1999) Biochemistry 38: 6953-6961

Released	1999-06-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli K-12
Macromolecule	PROTEIN (ADENYLOSUCCINATE SYNTHETASE) (protein)
Unique Ligands	GDP, HDA, IMO, MG

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1CG3 \| pdb_00001cg3	Download File View File

STRUCTURE OF THE MUTANT (R143L) OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH HADACIDIN, GDP, 6-PHOSPHORYL-IMP, AND MG2+

Choe, J.Y., Poland, B.W., Fromm, H., Honzatko, R.

(1999) Biochemistry 38: 6953-6961

Released	1999-06-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli K-12
Macromolecule	PROTEIN (ADENYLOSUCCINATE SYNTHETASE) (protein)
Unique Ligands	GDP, HDA, IMO, MG

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1CG4 \| pdb_00001cg4	Download File View File

STRUCTURE OF THE MUTANT (R303L) OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH, GDP, 6-PHOSPHORYL-IMP, AND MG2+

Choe, J.Y., Poland, B.W., Fromm, H., Honzatko, R.

(1999) Biochemistry 38: 6953-6961

Released	1999-06-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli K-12
Macromolecule	PROTEIN (ADENYLOSUCCINATE SYNTHETASE) (protein)
Unique Ligands	GDP, IMO, MG

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1CH8 \| pdb_00001ch8	Download File View File

STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH A STRINGENT EFFECTOR, PPG2':3'P

Hou, Z., Cashel, M., Fromm, H.J., Honzatko, R.B.

(1999) J Biological Chem 274: 17505-17510

Released	1999-12-29
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli K-12
Macromolecule	PROTEIN (ADENYLOSUCCINATE SYNTHETASE) (protein)
Unique Ligands	GPX, HDA, IMP, MG, NO3

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1CIB \| pdb_00001cib	Download File View File

STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH GDP, IMP, HADACIDIN, AND NO3

Hou, Z., Cashel, M., Fromm, H.J., Honzatko, R.B.

(1999) J Biological Chem 274: 17505-17510

Released	2000-04-05
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli K-12
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GDP, HDA, IMP, MG, NO3

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1DJ2 \| pdb_00001dj2	Download File View File

STRUCTURES OF ADENYLOSUCCINATE SYNTHETASE FROM TRITICUM AESTIVUM AND ARABIDOPSIS THALIANA

Prade, L., Cowan-Jacob, S.W., Chemla, P., Potter, S., Ward, E., Fonne-Pfister, R.

(2000) J Mol Biology 296: 569-577

Released	2000-03-24
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Arabidopsis thaliana
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GDP

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1DJ3 \| pdb_00001dj3	Download File View File

STRUCTURES OF ADENYLOSUCCINATE SYNTHETASE FROM TRITICUM AESTIVUM AND ARABIDOPSIS THALIANA

Prade, L., Cowan-Jacob, S.W., Chemla, P., Potter, S., Ward, E., Fonne-Pfister, R.

(2000) J Mol Biology 296: 569-577

Released	2000-03-24
Method	X-RAY DIFFRACTION 3 Å
Organisms	Triticum aestivum
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GDP

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1GIM \| pdb_00001gim	Download File View File

CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH GDP, IMP, HADACIDIN, NO3-, AND MG2+. DATA COLLECTED AT 100K (PH 6.5)

Poland, B.W., Fromm, H.J., Honzatko, R.B.

(1996) J Mol Biology 264: 1013-1027

Released	1996-12-23
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GDP, HDA, IMP, MG, NO3

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1GIN \| pdb_00001gin	Download File View File

CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH GDP, IMP, HADACIDIN, NO3-, AND MG2+. DATA COLLECTED AT 298K (PH 6.5).

Poland, B.W., Fromm, H.J., Honzatko, R.B.

(1996) J Mol Biology 264: 1013-1027

Released	1997-02-12
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GDP, HDA, IMP, MG, NO3

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1HON \| pdb_00001hon	Download File View File

STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREE CELSIUS

Poland, B.W., Hou, Z., Bruns, C., Fromm, H.J., Honzatko, R.B.

(1996) J Biological Chem 271: 15407-15413

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GNH

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1HOO \| pdb_00001hoo	Download File View File

STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI AT PH 6.5 AND 25 DEGREES CELSIUS

Poland, B.W., Hou, Z., Bruns, C., Fromm, H.J., Honzatko, R.B.

(1996) J Biological Chem 271: 15407-15413

Released	1997-02-12
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GNH, GNP

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1HOP \| pdb_00001hop	Download File View File

STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREES CELSIUS

Poland, B.W., Hou, Z., Bruns, C., Fromm, H.J., Honzatko, R.B.

(1996) J Biological Chem 271: 15407-15413

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GCP

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1IWE \| pdb_00001iwe	Download File View File

IMP Complex of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase

Iancu, C.V., Borza, T., Fromm, H.J., Honzatko, R.B.

(2002) J Biological Chem 277: 26779-26787

Released	2002-08-28
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Mus musculus
Macromolecule	Adenylosuccinate Synthetase (protein)
Unique Ligands	ACT, IMP, MG

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1J4B \| pdb_00001j4b	Download File View File

Recombinant Mouse-Muscle Adenylosuccinate Synthetase

Iancu, C.V., Borza, T., Choe, J.Y., Fromm, H.J., Honzatko, R.B.

(2001) J Biological Chem 276: 42146-42152

Released	2001-11-21
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Mus musculus
Macromolecule	adenylosuccinate synthetase (protein)

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1JUY \| pdb_00001juy	Download File View File

REFINED CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH HYDANTOCIDIN 5'-PHOSPHATE GDP, HPO4(2-), MG2+, AND HADACIDIN

Poland, B.W., Lee, S.-F., Subramanian, M.V., Siehl, D.L., Anderson, R.J., Fromm, H.J., Honzatko, R.B.

(1996) Biochemistry 35: 15753-15759

Released	1997-06-24
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GDP, H5P, HDA, MG, PI

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1KJX \| pdb_00001kjx	Download File View File

IMP Complex of E. Coli Adenylosuccinate Synthetase

Hou, Z., Wang, W., Fromm, H.J., Honzatko, R.B.

(2002) J Biological Chem 277: 5970-5976

Released	2002-03-20
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Escherichia coli K-12
Macromolecule	Adenylosuccinate Synthetase (protein)
Unique Ligands	IMP

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1KKB \| pdb_00001kkb	Download File View File

Complex of Escherichia coli Adenylosuccinate Synthetase with IMP and Hadacidin

Hou, Z., Wang, W., Fromm, H.J., Honzatko, R.B.

(2002) J Biological Chem 277: 5970-5976

Released	2002-03-20
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Escherichia coli K-12
Macromolecule	Adenylosuccinate Synthetase (protein)
Unique Ligands	HDA, IMP

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1KKF \| pdb_00001kkf	Download File View File

Complex of E. coli Adenylosuccinate Synthetase with IMP, Hadacidin, Pyrophosphate, and Mg

Hou, Z., Wang, W., Fromm, H.J., Honzatko, R.B.

(2002) J Biological Chem 277: 5970-5976

Released	2002-03-20
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Escherichia coli K-12
Macromolecule	Adenylosuccinate Synthetase (protein)
Unique Ligands	DPO, HDA, IMP, MG

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1KSZ \| pdb_00001ksz	Download File View File

ENTRAPMENT OF 6-THIOPHOSPHORYL-IMP IN THE ACTIVE SITE OF CRYSTALLINE ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI, DATA COLLECTED AT 298K

Poland, B.W., Bruns, C.A., Fromm, H.J., Honzatko, R.B.

(1997) J Biological Chem 272: 15200-15205

Released	1997-10-08
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GDP, HDA, MG, PGS

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1LNY \| pdb_00001lny	Download File View File

Crystal structure of the recombinant mouse-muscle adenylosuccinate synthetase complexed with 6-phosphoryl-IMP, GDP and Mg

Iancu, C.V., Borza, T., Fromm, H.J., Honzatko, R.B.

(2002) J Biological Chem 277: 26779-26787

Released	2002-08-28
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mus musculus
Macromolecule	Adenylosuccinate Synthetase (protein)
Unique Ligands	GDP, IMO, MG

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1LON \| pdb_00001lon	Download File View File

Crystal Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with 6-phosphoryl-IMP, GDP and Hadacidin

Iancu, C.V., Borza, T., Fromm, H.J., Honzatko, R.B.

(2002) J Biological Chem 277: 26779-26787

Released	2002-08-28
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Mus musculus
Macromolecule	adenylosuccinate synthetase (protein)
Unique Ligands	GDP, HDA, IMO, MG