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233,249 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: PubMed ID = 34128081

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Search Summary

This query matches 8 Structures.

Refinements

Structure Determination Methodology

experimental (8)

Scientific Name of Source Organism

	Mus musculus (7)
	Homo sapiens (6)
	Aequorea victoria (2)
	Rattus norvegicus (2)

Taxonomy

Eukaryota (8)

Experimental Method

	ELECTRON MICROSCOPY (5)
	X-RAY DIFFRACTION (3)

Polymer Entity Type

Protein (8)

Refinement Resolution (Å)

	2.0 - 2.5 (2)
	2.5 - 3.0 (3)
	3.0 - 3.5 (3)

Release Date

	2005 - 2009 (2)
	2010 - 2014 (1)
	2020 - 2024 (3)
	2025 - 2029 (2)

Enzyme Classification Name

Hydrolases (1)

Membrane Protein Annotation

	PDBTM (3)
	mpstruc (3)
	OPM (2)
	MemProtMD (1)

Symmetry Type

Asymmetric (8)

SCOP Classification

	All alpha proteins (3)
	Alpha and beta proteins (a/b) (1)

AllSelected

1 to 8 of 8 Structures

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3AB3 \| pdb_00003ab3	Download File View File

Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13

Kukimoto-Niino, M., Mishima, C., Shirouzu, M., Kozasa, T., Yokoyama, S.

(2011) J Biological Chem 286: 20625-20636

Released	2010-12-29
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Guanine nucleotide-binding protein G(k) subunit alpha, Guanine nucleotide-binding protein subunit alpha-13 (protein) Rho guanine nucleotide exchange factor 1 (protein)
Unique Ligands	ALF, GDP, MG

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3CX6 \| pdb_00003cx6	Download File View File

Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP

Sprang, S.R., Chen, Z.

(2008) Structure 16: 1532-1543

Released	2008-10-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Mus musculus Rattus norvegicus
Macromolecule	Guanine nucleotide-binding protein alpha-13 subunit (protein) Rho guanine nucleotide exchange factor 11 (protein)
Unique Ligands	GDP, MG

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3CX8 \| pdb_00003cx8	Download File View File

Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GTP-gamma-S

Sprang, S.R., Chen, Z.

(2008) Structure 16: 1532-1543

Released	2008-10-28
Method	X-RAY DIFFRACTION 2 Å
Organisms	Mus musculus Rattus norvegicus
Macromolecule	Guanine nucleotide-binding protein alpha-13 subunit (protein) Rho guanine nucleotide exchange factor 11 (protein)
Unique Ligands	GSP, MG

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7T6B \| pdb_00007t6b	Download File View File

Structure of S1PR2-heterotrimeric G13 signaling complex

Li, X., Chen, H.

(2022) Sci Adv 8: eabn0067-eabn0067

Released	2022-04-06
Method	ELECTRON MICROSCOPY 3.19 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (protein) Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (protein) Guanine nucleotide-binding protein subunit alpha-13 (protein) Sphingosine 1-phosphate receptor 2 (protein) scFv16 (protein)
Unique Ligands	S1P

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8H8J \| pdb_00008h8j	Download File View File

Lodoxamide-bound GPR35 in complex with G13

Yuan, Q., Duan, J., Liu, Q., Xu, H.E., Jiang, Y.

(2022) Cell Discov 8: 135-135

Released	2023-02-08
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	G-protein coupled receptor 35 (protein) Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (protein) Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (protein) Guanine nucleotide-binding protein subunit alpha-13 (protein) scFv16 (protein)
Unique Ligands	CA, CLR, WYB

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8KGG \| pdb_00008kgg	Download File View File

LPS-bound P2Y10 in complex with G13

He, Y., Yin, Y.

(2024) Cell Chem Biol 31: 1899-1908.e5

Released	2024-07-31
Method	ELECTRON MICROSCOPY 3.06 Å
Organisms	Homo sapiens
Macromolecule	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (protein) Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (protein) Guanine nucleotide-binding protein G(i) subunit alpha-2,Guanine nucleotide-binding protein subunit alpha-13 (protein) Putative P2Y purinoceptor 10 (protein) scFv16 (protein)
Unique Ligands	WJS

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9GE2 \| pdb_00009ge2	Download File View File

Structure of GPR55 in complex with G13 and synthetic agonist ML184

Claff, T., Ebenhoch, R., Weichert, D.

(2025) Nat Commun 16: 1973-1973

Released	2025-03-05
Method	ELECTRON MICROSCOPY 2.51 Å
Organisms	Aequorea victoria Homo sapiens Mus musculus
Macromolecule	Green fluorescent protein,G-protein coupled receptor 55 (protein) Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (protein) Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (protein) Guanine nucleotide-binding protein subunit alpha-13 (protein) Single-chain variable fragment ScFv16 (protein)
Unique Ligands	A1IKH, CLR
Unique branched monosaccharides	NAG

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9GE3 \| pdb_00009ge3	Download File View File

Structure of GPR55 in complex with G13 and endogenous lipid agonist lysophosphatidylinositol

Claff, T., Ebenhoch, R., Weichert, D.

(2025) Nat Commun 16: 1973-1973

Released	2025-03-05
Method	ELECTRON MICROSCOPY 2.87 Å
Organisms	Aequorea victoria Homo sapiens Mus musculus
Macromolecule	Green fluorescent protein,G-protein coupled receptor 55 (protein) Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (protein) Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (protein) Guanine nucleotide-binding protein subunit alpha-13 (protein) Single-chain variable fragment ScFv16 (protein)
Unique Ligands	A1IKT, NAG

1 to 8 of 8 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

3AB3 | pdb_00003ab3

Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13

3CX6 | pdb_00003cx6

Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP

3CX8 | pdb_00003cx8

Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GTP-gamma-S

7T6B | pdb_00007t6b

Structure of S1PR2-heterotrimeric G13 signaling complex

8H8J | pdb_00008h8j

Lodoxamide-bound GPR35 in complex with G13

8KGG | pdb_00008kgg

LPS-bound P2Y10 in complex with G13

9GE2 | pdb_00009ge2

Structure of GPR55 in complex with G13 and synthetic agonist ML184

9GE3 | pdb_00009ge3

Structure of GPR55 in complex with G13 and endogenous lipid agonist lysophosphatidylinositol

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

3AB3 | pdb_00003ab3

3CX6 | pdb_00003cx6

3CX8 | pdb_00003cx8

7T6B | pdb_00007t6b

8H8J | pdb_00008h8j

8KGG | pdb_00008kgg

9GE2 | pdb_00009ge2

9GE3 | pdb_00009ge3