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233,249 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Valentin Gese, G."

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Search Summary

This query matches 18 Structures.

Refinements

Structure Determination Methodology

experimental (18)

Scientific Name of Source Organism

	Homo sapiens (16)
	Thermochaetoides thermophila DSM 1495 (2)

Taxonomy

Eukaryota (18)

Experimental Method

	ELECTRON MICROSCOPY (16)
	X-RAY DIFFRACTION (2)

Polymer Entity Type

	Protein (18)
	RNA (12)

Refinement Resolution (Å)

	1.5 - 2.0 (1)
	2.0 - 2.5 (1)
	2.5 - 3.0 (9)
	3.0 - 3.5 (4)
	3.5 - 4.0 (1)
	4.0 - 4.5 (1)
	> 4.5 (1)

Release Date

	2015 - 2019 (1)
	2020 - 2024 (17)

Enzyme Classification Name

	Oxidoreductases (4)
	Transferases (7)
	Hydrolases (9)

Symmetry Type

	Asymmetric (16)
	Cyclic (1)
	Helical (1)

AllSelected

1 to 18 of 18 Structures

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5MB9 \| pdb_00005mb9	Download File View File

Crystal structure of the eukaryotic ribosome associated complex (RAC), a unique Hsp70/Hsp40 pair

Gumiero, A., Weyer, F.A., Valentin Gese, G., Lapouge, K., Sinning, I.

(2017) Nat Struct Mol Biol 24: 144-151

Released	2016-12-28
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Thermochaetoides thermophila DSM 1495
Macromolecule	Putative heat shock protein (protein) Putative ribosome associated protein (protein)
Unique Ligands	ATP, GOL, MG

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6SR6 \| pdb_00006sr6	Download File View File

Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD

Valentin Gese, G., Lapouge, K., Kopp, J., Sinning, I.

(2020) Nat Commun 11: 1504-1504

Released	2020-03-25
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Thermochaetoides thermophila DSM 1495
Macromolecule	Putative heat shock protein (protein) Putative ribosome associated protein (protein)
Unique Ligands	ATP, MG

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7O9K \| pdb_00007o9k	Download File View File

Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu

Valentin Gese, G., Hallberg, B.M.

(2021) Nat Commun 12: 3673-3673

Released	2021-06-30
Method	ELECTRON MICROSCOPY 3.1 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 61 Unique nucleic acid chains: 2
Unique Ligands	GDP, GTP, MG, PNS, SAH, SAM, ZN

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7O9M \| pdb_00007o9m	Download File View File

Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and the MALSU module

Valentin Gese, G., Hallberg, B.M.

(2021) Nat Commun 12: 3673-3673

Released	2021-06-30
Method	ELECTRON MICROSCOPY 2.6 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 59 Unique nucleic acid chains: 2
Unique Ligands	GDP, MG, PNS, SAM, ZN

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7P09 \| pdb_00007p09	Download File View File

Human mitochondrial Lon protease with substrate in the ATPase domain

Valentin Gese, G., Shahzad, S., Hallberg, B.M.

To be published

Released	2021-08-11
Method	ELECTRON MICROSCOPY 2.7 Å
Organisms	Homo sapiens
Macromolecule	Lon protease homolog, mitochondrial (protein) Unknown peptide from human mitochondrial transcription factor A (TFAM) (protein)
Unique Ligands	ADP, ATP, MG

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7P0B \| pdb_00007p0b	Download File View File

Human mitochondrial Lon protease without substrate

Valentin Gese, G., Shahzad, S., Hallberg, B.M.

To be published

Released	2021-08-11
Method	ELECTRON MICROSCOPY 4.11 Å
Organisms	Homo sapiens
Macromolecule	Lon protease homolog, mitochondrial (protein)
Unique Ligands	ADP

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7P0M \| pdb_00007p0m	Download File View File

Human mitochondrial Lon protease with substrate in the ATPase and protease domains

Valentin Gese, G., Shahzad, S., Hallberg, B.M.

To be published

Released	2021-08-11
Method	ELECTRON MICROSCOPY 2.75 Å
Organisms	Homo sapiens
Macromolecule	Lon protease homolog, mitochondrial (protein) Unknown peptide from human mitochondrial transcription factor A (TFAM) (protein)
Unique Ligands	ADP, ATP, MG

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8AS5 \| pdb_00008as5	Download File View File

CryoEM structure of the human Nucleophosmin 1 core

Valentin Gese, G., Hallberg, B.M.

(2023) PNAS Nexus 2: pgac303-pgac303

Released	2023-02-15
Method	ELECTRON MICROSCOPY 3.53 Å
Organisms	Homo sapiens
Macromolecule	Nucleophosmin (protein)

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8QRK \| pdb_00008qrk	Download File View File

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 1

Valentin Gese, G., Cipullo, M., Rorbach, J., Hallberg, B.M.

(2024) Nat Commun 15: 5664-5664

Released	2024-06-26
Method	ELECTRON MICROSCOPY 6.69 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 29 Unique nucleic acid chains: 1
Unique Ligands	ATP, FES, GNP, K, MG, NAD, SPM, SRY, ZN

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8QRL \| pdb_00008qrl	Download File View File

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 2

Valentin Gese, G., Cipullo, M., Rorbach, J., Hallberg, B.M.

(2024) Nat Commun 15: 5664-5664

Released	2024-06-26
Method	ELECTRON MICROSCOPY 3.34 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 30 Unique nucleic acid chains: 1
Unique Ligands	ATP, FES, GDP, K, MG, NAD, SAH, ZN

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8QRM \| pdb_00008qrm	Download File View File

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3

Valentin Gese, G., Cipullo, M., Rorbach, J., Hallberg, B.M.

(2024) Nat Commun 15: 5664-5664

Released	2024-06-26
Method	ELECTRON MICROSCOPY 3.05 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 31 Unique nucleic acid chains: 1
Unique Ligands	ATP, FES, GNP, K, MG, NAD, SPM, SRY, ZN

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8QRN \| pdb_00008qrn	Download File View File

mt-SSU in GTPBP8 knock-out cells, state 4

Valentin Gese, G., Cipullo, M., Rorbach, J., Hallberg, B.M.

(2024) Nat Commun 15: 5664-5664

Released	2024-06-26
Method	ELECTRON MICROSCOPY 2.98 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 31 Unique nucleic acid chains: 3
Unique Ligands	ATP, FES, FME, GNP, GTP, K, MG, NAD, SPM, SRY, ZN

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8QU1 \| pdb_00008qu1	Download File View File

mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 1

Valentin Gese, G., Cipullo, M., Rorbach, J., Hallberg, B.M.

(2024) Nat Commun 15: 5664-5664

Released	2024-06-26
Method	ELECTRON MICROSCOPY 2.74 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 28 Unique nucleic acid chains: 2

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8QU5 \| pdb_00008qu5	Download File View File

mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 2

Valentin Gese, G., Cipullo, M., Rorbach, J., Hallberg, B.M.

(2024) Nat Commun 15: 5664-5664

Released	2024-06-26
Method	ELECTRON MICROSCOPY 2.42 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 53 Unique nucleic acid chains: 2
Unique Ligands	MG, PNS, ZN

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9EY0 \| pdb_00009ey0	Download File View File

Human mitochondrial RNase Z with tRNA-His

Valentin Gese, G., Hallberg, B.M.

(2024) EMBO J 43: 6573-6590

Released	2024-11-13
Method	ELECTRON MICROSCOPY 2.78 Å
Organisms	Homo sapiens
Macromolecule	3-hydroxyacyl-CoA dehydrogenase type-2 (protein) Zinc phosphodiesterase ELAC protein 2 (protein) tRNA methyltransferase 10 homolog C (protein) mt-tRNA-His (nucleic acid)
Unique Ligands	GTP, SAM, ZN

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9EY1 \| pdb_00009ey1	Download File View File

Human mitochondrial RNase Z with tRNA-His precursor

Valentin Gese, G., Hallberg, B.M.

(2024) EMBO J 43: 6573-6590

Released	2024-11-13
Method	ELECTRON MICROSCOPY 2.9 Å
Organisms	Homo sapiens
Macromolecule	3-hydroxyacyl-CoA dehydrogenase type-2 (protein) Zinc phosphodiesterase ELAC protein 2 (protein) tRNA methyltransferase 10 homolog C (protein) tRNA-His-tRNA-Ser (nucleic acid)
Unique Ligands	GTP, SAH, ZN

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9EY2 \| pdb_00009ey2	Download File View File

Human mitochondrial RNase Z with tRNA-His-CCA

Valentin Gese, G., Hallberg, B.M.

(2024) EMBO J 43: 6573-6590

Released	2024-11-27
Method	ELECTRON MICROSCOPY 2.96 Å
Organisms	Homo sapiens
Macromolecule	3-hydroxyacyl-CoA dehydrogenase type-2 (protein) Zinc phosphodiesterase ELAC protein 2 (protein) tRNA methyltransferase 10 homolog C (protein) mt-tRNA-His-CCA (nucleic acid)
Unique Ligands	GTP, SAM, ZN

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9GCH \| pdb_00009gch	Download File View File

Human mitochondrial RNase Z with tRNA-His-CCA, SDR5C1/TRMT10C focus

Valentin Gese, G., Hallberg, B.M.

(2024) EMBO J 43: 6573-6590

Released	2024-11-20
Method	ELECTRON MICROSCOPY 1.9 Å
Organisms	Homo sapiens
Macromolecule	3-hydroxyacyl-CoA dehydrogenase type-2 (protein) tRNA methyltransferase 10 homolog C (protein) mt-tRNA-His-CCA (nucleic acid)
Unique Ligands	GTP, MG, SAM

1 to 18 of 18 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

5MB9 | pdb_00005mb9

Crystal structure of the eukaryotic ribosome associated complex (RAC), a unique Hsp70/Hsp40 pair

6SR6 | pdb_00006sr6

Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD

7O9K | pdb_00007o9k

Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu

7O9M | pdb_00007o9m

Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and the MALSU module

7P09 | pdb_00007p09

Human mitochondrial Lon protease with substrate in the ATPase domain

7P0B | pdb_00007p0b

Human mitochondrial Lon protease without substrate

7P0M | pdb_00007p0m

Human mitochondrial Lon protease with substrate in the ATPase and protease domains

8AS5 | pdb_00008as5

CryoEM structure of the human Nucleophosmin 1 core

8QRK | pdb_00008qrk

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 1

8QRL | pdb_00008qrl

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 2

8QRM | pdb_00008qrm

mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3

8QRN | pdb_00008qrn

mt-SSU in GTPBP8 knock-out cells, state 4

8QU1 | pdb_00008qu1

mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 1

8QU5 | pdb_00008qu5

mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 2

9EY0 | pdb_00009ey0

Human mitochondrial RNase Z with tRNA-His

9EY1 | pdb_00009ey1

Human mitochondrial RNase Z with tRNA-His precursor

9EY2 | pdb_00009ey2

Human mitochondrial RNase Z with tRNA-His-CCA

9GCH | pdb_00009gch

Human mitochondrial RNase Z with tRNA-His-CCA, SDR5C1/TRMT10C focus

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

5MB9 | pdb_00005mb9

6SR6 | pdb_00006sr6

7O9K | pdb_00007o9k

7O9M | pdb_00007o9m

7P09 | pdb_00007p09

7P0B | pdb_00007p0b

7P0M | pdb_00007p0m

8AS5 | pdb_00008as5

8QRK | pdb_00008qrk

8QRL | pdb_00008qrl

8QRM | pdb_00008qrm

8QRN | pdb_00008qrn

8QU1 | pdb_00008qu1

8QU5 | pdb_00008qu5

9EY0 | pdb_00009ey0

9EY1 | pdb_00009ey1

9EY2 | pdb_00009ey2

9GCH | pdb_00009gch